TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice

L Wang, DH Wang - Circulation, 2005 - Am Heart Assoc
Background—Although pharmacological studies suggest that the transient receptor potential
vanilloid type 1 (TRPV1) channels expressed in sensory nerve fibers innervating the heart …

—Current Perspective—Actions of Tachykinins Within the Heart and Their Relevance to Cardiovascular Disease

DB Hoover, Y Chang, JC Hancock… - The Japanese Journal of …, 2000 - jstage.jst.go.jp
抄録 Substance P and neurokinin A are tachykinins that are co-localized with calcitonin
gene-related peptide (CGRP) in a unique subpopulation of cardiac afferent nerve fibers …

Tachykinins and the cardiovascular system

DA Walsh, DF McWilliams - Current drug targets, 2006 - ingentaconnect.com
The tachykinin family of vasoactive peptides comprises the neuropeptides substance P,
neurokinin A and neurokinin B, and the newly discovered endokinins and hemokinins. Their …

Serum levels of calcitonin gene-related peptide and substance P are decreased in patients with diabetes mellitus and coronary artery disease

LH Wang, SX Zhou, RC Li, LR Zheng… - Journal of …, 2012 - journals.sagepub.com
OBJECTIVE: This study evaluated serum levels of the neuropeptides calcitonin gene-related
peptide (CGRP) and substance P (SP) in coronary artery disease (CAD) patients with and …

Co-variation of neuropeptide Y, calcitonin gene-related peptide, substance P and neurokinin A in joint fluid from patients with temporomandibular joint arthritis

P Alstergren, A Appelgren, B Appelgren, S Kopp… - Archives of oral …, 1995 - Elsevier
Forty-one patients (37 female and four male) with signs and symptoms of
temporomandibular joint arthritis, were separated into two diagnostic groups (group I …

The depressor and vasodilator effects of rutaecarpine are mediated by calcitonin gene-related peptide

CP Hu, L Xiao, HW Deng, YJ Li - Planta medica, 2003 - thieme-connect.com
Previous studies have shown that rutaecarpine has depressor and vasodilator effects, and
activates vanilloid receptors to evoke calcitonin gene-related peptide (CGRP) release. In the …

Neuropeptide depletion impairs postischemic recovery of the isolated rat heart: role of substance P

EE Ustinova, D Bergren, HD Schultz - Cardiovascular research, 1995 - academic.oup.com
Objectives: Ischemia of the myocardium stimulates cardiac sensory nerve endings resulting
in the local release of neuropeptides. The significance of the release of neuropeptides, such …

The role of neuropeptides in adverse myocardial remodeling and heart failure

A Widiapradja, P Chunduri, SP Levick - Cellular and Molecular Life …, 2017 - Springer
In addition to traditional neurotransmitters of the sympathetic and parasympathetic nervous
systems, the heart also contains numerous neuropeptides. These neuropeptides not only …

Canine intrinsic cardiac neurons involved in cardiac regulation possess NK1, NK2, and NK3 receptors

GW Thompson, DB Hoover… - American Journal of …, 1998 - journals.physiology.org
To determine whether intrinsic cardiac neurons involved in cardiac regulation possess
neurokinin (NK) receptor subtypes, we administered selective NK receptor agonists …

The depressor effect of nitroglycerin is mediated by calcitonin gene-related peptide

ZH Zhou, HW Deng, YJ Li - Life Sciences, 2001 - Elsevier
Previous investigations have suggested that vasodilator responses to nitroglycerin involve in
stimulation of calcitonin gene-related peptide (CGRP) release. Therefore, we tested whether …