Sex effects across the lifespan in women with multiple sclerosis

KM Krysko, JS Graves, R Dobson… - Therapeutic …, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating central nervous
system disorder that is more common in women, with onset often during reproductive years …

Impact of age on multiple sclerosis disease activity and progression

B Zeydan, OH Kantarci - Current neurology and neuroscience reports, 2020 - Springer
Abstract Purpose of Review The purpose of this review is to discuss the interaction between
aging, progressive disease course, disability worsening, and treatment strategies in multiple …

[HTML][HTML] Aging in multiple sclerosis: From childhood to old age, etiopathogenesis, and unmet needs: A narrative review

N Capasso, E Virgilio, A Covelli, B Giovannini… - Frontiers in …, 2023 - frontiersin.org
Multiple sclerosis (MS) primarily affects adult females. However, in the last decades, rising
incidence and prevalence have been observed for demographic extremes, such as pediatric …

Reproductive history and progressive multiple sclerosis risk in women

B Zeydan, EJ Atkinson, DM Weis, CY Smith… - Brain …, 2020 - academic.oup.com
Being a woman is one of the strongest risk factors for multiple sclerosis. The natural
reproductive period from menarche to natural menopause corresponds to the active …

Effects of the menstrual cycle on neurological disorders

HJ Roeder, EC Leira - Current neurology and neuroscience reports, 2021 - Springer
Abstract Purpose of Review The menstrual cycle involves recurrent fluctuations in hormone
levels and temperature via neuroendocrine feedback loops. This paper reviews the impact …

[HTML][HTML] Effects of menopause in women with multiple sclerosis: an evidence-based review

R Bove, A Okai, M Houtchens, B Elias-Hamp… - Frontiers in …, 2021 - frontiersin.org
Over two thirds of all individuals who develop multiple sclerosis (MS) will be women prior to
the age of menopause. Further, an estimated 30% of the current MS population consists of …

[HTML][HTML] Sex bias in multiple sclerosis and neuromyelitis optica spectrum disorders: how it influences clinical course, MRI parameters and prognosis

P Nytrova, O Dolezal - Frontiers in immunology, 2022 - frontiersin.org
This review is a condensed summary of representative articles addressing the sex/gender
bias in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). The …

[HTML][HTML] Menopausal transition in multiple sclerosis: relationship with disease activity and brain volume measurements

L Lorefice, G Fenu, M Fronza, F Murgia, J Frau… - Frontiers in …, 2023 - frontiersin.org
Background Recent evidence has shown a significant association between menopause and
multiple sclerosis (MS) progression. This study investigated the possible role of menopause …

The role of sex hormones in women with multiple sclerosis: From puberty to assisted reproductive techniques

M Sparaco, S Bonavita - Frontiers in Neuroendocrinology, 2021 - Elsevier
Abstract Background Multiple Sclerosis is a multifactorial chronic autoimmune disease,
affecting predominantly females in the fertile age. Sex hormones changes during a woman's …

[HTML][HTML] Impact of menopause on relapse rate and disability level in patients with multiple sclerosis (MS): a systematic review and meta-analysis

Z Shahraki, M Rastkar, E Rastkar, M Mohammadifar… - BMC neurology, 2023 - Springer
Background Menopause is a physiologic phase in women's lives. Findings regarding
multiple sclerosis (MS) course through menopause are diverse. So, we designed this …