Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

[HTML][HTML] Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

[HTML][HTML] Sex differences in pharmacokinetics predict adverse drug reactions in women

I Zucker, BJ Prendergast - Biology of sex differences, 2020 - Springer
Background Women experience adverse drug reactions, ADRs, nearly twice as often as
men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood …

[HTML][HTML] Sex-gender variable: methodological recommendations for increasing scientific value of clinical studies

F Franconi, I Campesi, D Colombo, P Antonini - Cells, 2019 - mdpi.com
There is a clear sex–gender gap in the prevention and occurrence of diseases, and in the
outcomes and treatments, which is relevant to women in the majority of cases. Attitudes …

Adverse events: race, inequality, and the testing of new pharmaceuticals

JA Fisher - Adverse Events, 2020 - degruyter.com
Imagine that you volunteer for the clinical trial of an experimental drug. The only direct
benefit of participating is that you will receive up to $5,175. You must spend twenty nights …

[HTML][HTML] Are sex and gender considered in head and neck cancer clinical studies?

A Gaeta, M Tagliabue, O D'Ecclesiis, L Ghiani… - NPJ Precision …, 2023 - nature.com
We analyzed the inclusion of sex and/or gender (S/G) in Head and Neck Cancer (HNC)
clinical studies, through inspecting ClinicalTrials. gov (AACT) and the mention of Human …

[HTML][HTML] How to study the impact of sex and gender in medical research: a review of resources

AJ McGregor, M Hasnain, K Sandberg… - Biology of sex …, 2016 - Springer
There is a growing appreciation by the biomedical community that studying the impact of sex
and gender on health, aging, and disease will lead to improvements in human health. Sex …

[HTML][HTML] “Saving lives”: adapting and adopting human papilloma virus (HPV) vaccination in Austria

KT Paul - Social Science & Medicine, 2016 - Elsevier
Vaccination against the sexually transmitted Human Papilloma Virus (HPV), a necessary
agent for the development of cervical cancer, has triggered much debate. In Austria, HPV …

Feeding and bleeding: The institutional banalization of risk to healthy volunteers in phase I pharmaceutical clinical trials

JA Fisher - Science, Technology, & Human Values, 2015 - journals.sagepub.com
Phase I clinical trials are the first stage of testing new pharmaceuticals in humans. The
majority of these studies are conducted under controlled, inpatient conditions using healthy …

[HTML][HTML] Sex, Gender, and the Regulation of Prescription Drugs: Omissions and Opportunities

L Greaves, AC Brabete, M Maximos, E Huber… - International Journal of …, 2023 - mdpi.com
The regulation of prescription drugs is an important health, safety, and equity issue.
However, regulatory processes do not always consider evidence on sex, gender, and factors …