Epstein-Barr virus: Biology and clinical disease

B Damania, SC Kenney, N Raab-Traub - Cell, 2022 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

[HTML][HTML] Epstein–Barr virus: diseases linked to infection and transformation

HC Jha, Y Pei, ES Robertson - Frontiers in microbiology, 2016 - frontiersin.org
Epstein–Barr virus (EBV) was first discovered in 1964, and was the first known human tumor
virus now shown to be associated with a vast number of human diseases. Numerous studies …

EBV and apoptosis: the viral master regulator of cell fate?

L Fitzsimmons, GL Kelly - Viruses, 2017 - mdpi.com
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma
(BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are …

[HTML][HTML] EBV infection and its regulated metabolic reprogramming in nasopharyngeal tumorigenesis

T Yang, C You, S Meng, Z Lai, W Ai… - Frontiers in Cellular and …, 2022 - frontiersin.org
Viral oncogenes may drive cellular metabolic reprogramming to modulate the normal
epithelia cells malignant transformation. Understanding the viral oncogenes-mediated …

EBV infection and glucose metabolism in nasopharyngeal carcinoma

J Zhang, L Jia, CM Tsang, SW Tsao - Infectious Agents Associated …, 2017 - Springer
To establish persistent infection in cells, viruses evolve strategies to alter host cellular
pathways to regulate cell proliferation and energy metabolism which support viral infection …

Nasopharyngeal carcinoma: The role of the EGFR in epstein–barr virus infection

X Peng, Y Zhou, Y Tao, S Liu - Pathogens, 2021 - mdpi.com
Epstein–Barr virus (EBV), a type 4 γ herpes virus, is recognized as a causative agent in
nasopharyngeal carcinoma (NPC). Incidence of EBV-positive NPC have grown in recent …

Sputum cell IL-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients

MD Evans, S Esnault, LC Denlinger… - Journal of Allergy and …, 2018 - Elsevier
Background Various clinical, biologic, or physiologic markers of asthma have been used to
identify patient clusters and potential targets for therapy. However, these identifiers …

SSTR2 in Nasopharyngeal carcinoma: relationship with latent EBV infection and potential as a therapeutic target

O Emanuel, J Liu, VH Schartinger, WL Nei, YY Chan… - Cancers, 2021 - mdpi.com
Simple Summary Nasopharyngeal cancer (NPC) is a malignant epithelial tumor endemic to
parts of Asia and associated with infection by the Epstein–Barr virus (EBV) in these regions …

Characterization of target gene regulation by the two Epstein-Barr virus oncogene LMP1 domains essential for B-cell transformation

B Mitra, NR Beri, R Guo, EM Burton, LA Murray-Nerger… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT The Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1)
mimics CD40 signaling and is expressed by multiple malignancies. Two LMP1 C-terminal …

Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-κB signaling pathway

F Fredericksen, G Carrasco, M Villalba… - Molecular immunology, 2015 - Elsevier
The bovine viral diarrhea virus (BVDV-1) is a pathogen responsible for high economic
losses in the cattle industry worldwide. This virus has the capacity to modulate the immune …