Intrinsic networks regulating tissue repair: comparative studies of oral and skin wound healing

AM Overmiller, AP Sawaya… - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Wound repair is a systematic biological program characterized by four overlapping phases:
hemostasis, inflammation, proliferation, and remodeling. Notwithstanding differences …

Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration

N Prakash - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
The degeneration of dopaminergic and other neurons in the aging brain is considered a
process starting well beyond the infantile and juvenile period. In contrast to other dopamine …

Exome sequencing in 16 patients with pituitary stalk interruption syndrome: A monocentric study

R Brauner, J Bignon-Topalovic, A Bashamboo… - PLoS …, 2023 - journals.plos.org
Pituitary stalk interruption syndrome (PSIS) is a rare disorder characterized by an absent or
ectopic posterior pituitary, absent or interrupted pituitary stalk and anterior pituitary …

[HTML][HTML] PITX2 in pancreatic stellate cells promotes EMT in pancreatic cancer cells via the Wnt/β-catenin pathway: PITX2 promotes pancreatic cancer progression via …

D Wu, W Chen, Y Yang, Y Qin, G Zu… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
Since the prognosis of patients with pancreatic cancer is very poor and there is a lack of
treatment methods, this study is performed to investigate the function of PITX2 in pancreatic …

CellNeighborEX: deciphering neighbor‐dependent gene expression from spatial transcriptomics data

H Kim, A Kumar, C Lövkvist, AM Palma… - Molecular Systems …, 2023 - embopress.org
Cells have evolved their communication methods to sense their microenvironments and
send biological signals. In addition to communication using ligands and receptors, cells use …

CRISPR/Cas9 System-Mediated Gene Editing in the Fujian Oysters (Crassostrea angulate) by Electroporation

K Jin, B Zhang, Q Jin, Z Cai, L Wei, X Wang… - Frontiers in Marine …, 2021 - frontiersin.org
The Fujian oyster (Crassostrea angulate) is an important marine bivalve mollusk with high
economic value. Gene function research and gene editing techniques have broad …

Genetic factors that affect asymmetric mandibular growth—A systematic review

A Babczyńska, B Kawala, M Sarul - Symmetry, 2022 - mdpi.com
Facial asymmetry is a feature that occurs to a greater or lesser extent in the general
population. As its severity is usually slight, facial asymmetry may not be noticeable to the …

A four-gene prognostic signature for predicting the overall survival of patients with lung adenocarcinoma

L Liu, H He, Y Peng, Z Yang, S Gao - PeerJ, 2021 - peerj.com
Background The prognosis of patients for lung adenocarcinoma (LUAD) is known to vary
widely; the 5-year overall survival rate is just 63% even for the pathological IA stage. Thus, in …

The expression and methylation of PITX genes is associated with the prognosis of head and neck squamous cell carcinoma

Y Zhao, J Zhao, M Zhong, Q Zhang, F Yan… - Frontiers in …, 2022 - frontiersin.org
Background: The PITX gene family, comprising PITX1, PITX2, and PITX3, is critical in
organogenesis and has been evolutionary conserved in animals. PITX genes are …

Genetic network analysis indicate that individuals affected by neurodevelopmental conditions have genetic variations associated with ophthalmologic alterations: A …

RN Shinsato, C Corrêa, RH Herai - Gene, 2024 - Elsevier
Abstract Changes in the nervous system are related to a wide range of mental disorders,
which include neurodevelopmental disorders (NDD) that are characterized by early onset …