Exposure to stress early in life has been associated with adult-onset comorbidities such as
chronic pain, metabolic dysregulation, obesity, and inactivity. We have established an early …

Obesity, a complex and multifactorial disease influenced by genetic, environmental, and
psychological factors, has reached epidemic proportions globally, posing a significant health …

Background: Adipose tissue dysfunction has been implicated in the pathophysiology of
Alzheimer's disease. However, the involvement of adipokines, particularly adiponectin …

Aging undergoes serious worsening of peripheral organs and vital physiological processes
including reproductive performances. Altered white adipose tissue and adipocyte …

Rationale: Prediabetes can be reversed through lifestyle intervention, but its main pathologic
hallmark, insulin resistance (IR), cannot be detected as conveniently as blood glucose …

Diabetes mellitus is a chronic, life-threatening metabolic disorder that occurs worldwide.
Despite an increase in the knowledge of the risk factors that are associated with diabetes …

In cells and tissues resistin affects IL-1β, IL-6, IL-8, IL-12 and TNF-α expression, thus
suggesting the existence of a multi-cytokine “resistin pathway”. We investigated whether …

As the population ages, more individuals are at risk of developing age-related chronic
diseases, often leading to death. Identifying individuals most at risk for developing multiple …

Adipose tissue is a target of Trypanosoma cruzi infection being a parasite reservoir during
the chronic phase in mice and humans. Previously, we reported that acute Trypanosoma …

Subcutaneous white adipose tissue (scWAT) is a dynamic storage and secretory organ that
regulates systemic homeostasis, yet the impact of endurance exercise training (ExT) and sex …