Beyond the joints, the extra-articular manifestations in rheumatoid arthritis

A Conforti, I Di Cola, V Pavlych, P Ruscitti… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is an inflammatory disease typically affecting the joints, but the
systemic inflammatory process may involve other tissues and organs. Many extra-articular …

[HTML][HTML] Risk factors for coronary artery disease

JC Brown, TE Gerhardt, E Kwon - 2020 - europepmc.org
Objectives: Review the risk factors for coronary artery disease. Outline screening
recommendations for coronary artery disease. Identify diet and exercise recommendations …

Obesity in autoimmune diseases: not a passive bystander

M Versini, PY Jeandel, E Rosenthal, Y Shoenfeld - Autoimmunity reviews, 2014 - Elsevier
In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

Physical activity and autoimmune diseases: Get moving and manage the disease

K Sharif, A Watad, NL Bragazzi, M Lichtbroun… - Autoimmunity …, 2018 - Elsevier
Physical activity, by definition, is any skeletal muscle body movement that results in energy
expenditure. In the last few decades, a plethora of scientific evidences have accumulated …

Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis

AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease
(CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …

Endothelial dysfunction in chronic inflammatory diseases

CM Steyers III, FJ Miller Jr - International journal of molecular sciences, 2014 - mdpi.com
Chronic inflammatory diseases are associated with accelerated atherosclerosis and
increased risk of cardiovascular diseases (CVD). As the pathogenesis of atherosclerosis is …

[HTML][HTML] Evidence for treating rheumatoid arthritis to target: results of a systematic literature search update

MA Stoffer, MM Schoels, JS Smolen… - Annals of the …, 2016 - ard.bmj.com
Objective A systematic literature review (SLR; 2009–2014) to compare a target-oriented
approach with routine management in the treatment of rheumatoid arthritis (RA) to allow an …

Impact of Janus kinase inhibitors on risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and meta-analysis of randomised controlled …

W Xie, Y Huang, S Xiao, X Sun, Y Fan… - Annals of the rheumatic …, 2019 - ard.bmj.com
Objectives To investigate the effect of Janus kinase inhibitors (Jakinibs) on cardiovascular
risk in adult patients with rheumatoid arthritis (RA) via a meta-analysis of randomised …

Chronic inflammatory disorders and risk of type 2 diabetes mellitus, coronary heart disease, and stroke: a population-based cohort study

A Dregan, J Charlton, P Chowienczyk, MC Gulliford - Circulation, 2014 - Am Heart Assoc
Background—This study sought to evaluate whether risks of diabetes mellitus and
cardiovascular disease are elevated across a range of organ-specific and multisystem …

Cellular and engineered organoids for cardiovascular models

D Thomas, S Choi, C Alamana, KK Parker… - Circulation …, 2022 - Am Heart Assoc
An ensemble of in vitro cardiac tissue models has been developed over the past several
decades to aid our understanding of complex cardiovascular disorders using a reductionist …