Structure, function, and biosynthesis of nickel‐dependent enzymes
M Alfano, C Cavazza - Protein Science, 2020 - Wiley Online Library
Nickel enzymes, present in archaea, bacteria, plants, and primitive eukaryotes are divided
into redox and nonredox enzymes and play key functions in diverse metabolic processes …
into redox and nonredox enzymes and play key functions in diverse metabolic processes …
An overview on the synthetic urease inhibitors with structure-activity relationship and molecular docking
W Yang, Q Feng, Z Peng, G Wang - European Journal of Medicinal …, 2022 - Elsevier
Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …
[HTML][HTML] Design and synthesis of new N-thioacylated ciprofloxacin derivatives as urease inhibitors with potential antibacterial activity
A new series of N-thioacylated ciprofloxacin 3a–n were designed and synthesized based on
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
[HTML][HTML] A review of enzyme-induced calcium carbonate precipitation applicability in the oil and gas industry
Enzyme-induced calcium carbonate precipitation (EICP) techniques are used in several
disciplines and for a wide range of applications. In the oil and gas industry, EICP is a …
disciplines and for a wide range of applications. In the oil and gas industry, EICP is a …
Optimized ebselen-based inhibitors of bacterial ureases with nontypical mode of action
K Macegoniuk, W Tabor, L Mazzei… - Journal of Medicinal …, 2023 - ACS Publications
Screening of 25 analogs of Ebselen, diversified at the N-aromatic residue, led to the
identification of the most potent inhibitors of Sporosarcina pasteurii urease reported to date …
identification of the most potent inhibitors of Sporosarcina pasteurii urease reported to date …
[HTML][HTML] A small-molecular inhibitor against Proteus mirabilis urease to treat catheter-associated urinary tract infections
Infection and blockage of indwelling urinary catheters is significant owing to its high
incidence rate and severe medical consequences. Bacterial enzymes are employed as …
incidence rate and severe medical consequences. Bacterial enzymes are employed as …
Rational development of bacterial ureases inhibitors
S Loharch, Ł Berlicki - The Chemical Record, 2022 - Wiley Online Library
Urease, an enzyme that catalyzes the hydrolysis of urea, is a virulence factor of various
pathogenic bacteria. In particular, Helicobacter pylori, that colonizes the digestive tract and …
pathogenic bacteria. In particular, Helicobacter pylori, that colonizes the digestive tract and …
[HTML][HTML] Effect of Urea-Calcium Sulfate Cocrystal Nitrogen Fertilizer on Sorghum Productivity and Soil N2O Emissions
Urea cocrystal materials have recently emerged as high nitrogen (N) content fertilizers with
low solubility capable of minimizing N loss and improving their use efficiency. However, their …
low solubility capable of minimizing N loss and improving their use efficiency. However, their …
Covalent inhibition of bacterial urease by bifunctional catechol-based phosphonates and phosphinates
A Pagoni, A Grabowiecka, W Tabor… - Journal of Medicinal …, 2020 - ACS Publications
In this study, a new class of bifunctional inhibitors of bacterial ureases, important molecular
targets for antimicrobial therapies, was developed. The structures of the inhibitors consist of …
targets for antimicrobial therapies, was developed. The structures of the inhibitors consist of …
QM/MM molecular dynamics simulations revealed catalytic mechanism of urease
Urease catalyzes the hydrolysis of urea to form ammonia and carbamate, inducing an
overall pH increase that affects both human health and agriculture. Inhibition, mutagenesis …
overall pH increase that affects both human health and agriculture. Inhibition, mutagenesis …