High‐throughput tandem‐microwell assay for ammonia repositions FDA‐Approved drugs to inhibit Helicobacter pylori urease

F Liu, J Yu, YX Zhang, F Li, Q Liu, Y Zhou… - The FASEB …, 2021 - Wiley Online Library
To date, little attempt has been made to develop new treatments for Helicobacter pylori (H.
pylori), although the community is aware of the shortage of treatments for H. pylori. In this …

细菌脲酶蛋白结构与催化机制

贺越, 赵圣国, 张晓音, 郑楠, 王加启 - 生物技术通报, 2020 - biotech.aiijournal.com
细菌脲酶催化尿素分解产生氨, 但是高脲酶活性会对人类健康, 农业, 环境等造成不利影响,
因此研究细菌脲酶特征和抑制脲酶活性具有重要科学意义. 随着分子生物学和结构生物学的快速 …

Adaptation of a continuous, calorimetric kinetic assay to study the agmatinase-catalyzed hydrolytic reaction

LA Wilson, D Garcia, MM Pedroso, BL Schulz… - Analytical …, 2020 - Elsevier
Ureohydrolases are members of the metallohydrolase family of enzymes. Here, a simple
continuous assay for agmatinase (AGM) activity was established by following the …

[PDF][PDF] Natural Urease Inhibitors Reduce the Severity of Disease Symptoms, Dependent on the Lifestyle of the Pathogens. J. Fungi 2023, 9, 708

L Aliyeva-Schnorr, C Schuster, HB Deising - 2023 - opendata.uni-halle.de
The development of new anti-ureolytic compounds is of great interest due to the newly
discovered role of urease inhibitors in crop protection. Purine degradation and the …

HOW RECYCLING URINE COULD HELP SAVE THE WORLD

G MA, OOS NEX - Nature, 2022 - nature.com
The efforts reach far beyond the confines of university labs. Waterless urinals connect to
basement treatment systems in offices in Oregon and the Netherlands. In Paris, there are …

Structure and catalytic mechanism of Bacterial urease protein

Y HE, S ZHAO, X ZHANG, N ZHENG… - Biotechnology …, 2020 - biotech.aiijournal.com
Bacterial urease catalyzes the efficient decomposition of urea to produce ammonia;
however, high activity of urease has negative influence on human healthy, agriculture …

Urease

L Mazzei, S Ciurli - Encyclopedia of Inorganic and Bioinorganic …, 2011 - Wiley Online Library
Urease catalyzes the hydrolysis of urea to ammonia and carbamate, with the latter
decomposing spontaneously to yield another molecule of ammonia and bicarbonate, in the …

Synergistic Effect of Urease and Nitrification Inhibitors in the Reduction of Ammonia Volatilization

A Hussain, N Jahan, Z Jabeen, KU Rehman… - Water, Air, & Soil …, 2021 - Springer
Nitrogen (N) is deficient in more than 90% of soils of Pakistan, mainly because of low
organic matter contents. The use of nitrogenous fertilizers is a common practice for …

High-throughput tandem-microwell assay for ammonia repositions FDA-Approved drugs to Helicobacter pylori infection

F Liu, J Yu, YX Zhang, F Li, Q Liu, Y Zhou, S Huang… - bioRxiv, 2021 - biorxiv.org
To date, little attempt has been made to develop new treatments for Helicobacter pylori (H.
pylori), although the community is aware of the shortage of treatments for H. pylori. In this …

Biophysical and Electrochemical studies of Carbon Monoxide Dehydrogenase: Towards the design of bio-electrocatalysts for the CO2-CO interconversion

U Contaldo - 2021 - theses.hal.science
CO2 metabolism plays a fundamental role in biology, as it represents a “building block” for
the synthesis of organic molecules in living organisms. On the other hand, the excessive …