B cell zone reticular cells (BRCs) form stable microenvironments that direct efficient humoral
immunity with B cell priming and memory maintenance being orchestrated across lymphoid …

Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture
and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive …

Fibroblastic reticular cells (FRCs) direct the interaction and activation of immune cells in
discrete microenvironments of lymphoid organs. Despite their important role in steering …

Fibroblastic reticular cells (FRCs) are a crucial part of the stromal cell infrastructure of
secondary lymphoid organs (SLOs). Lymphoid organ fibroblasts form specialized niches for …

The spleen is a compartmentalized organ that serves as a blood filter and safeguard of
systemic immune surveillance. Labyrinthine networks of fibroblastic stromal cells construct …

The spleen is a gatekeeper of systemic immunity where immune responses against blood-
borne pathogens are initiated and sustained. Non-haematopoietic stromal cells construct …

Located within red pulp cords, splenic red pulp macrophages (RPMs) are constantly
exposed to the blood flow, clearing senescent red blood cells (RBCs) and recycling iron …

Lymphoid organs guarantee productive immune cell interactions through the establishment
of distinct microenvironmental niches that are built by fibroblastic reticular cells (FRC). These …

Fibroblasts, derived from the embryonic mesenchyme, are a diverse array of cells with roles
in development, homeostasis, repair, and disease across tissues. In doing so, fibroblasts …

Fibroblastic reticular cells (FRCs) determine the organization of lymphoid organs and control
immune cell interactions. While the cellular and molecular mechanisms underlying FRC …