[HTML][HTML] Microsatellite instability: a review of what the oncologist should know

K Li, H Luo, L Huang, H Luo, X Zhu - Cancer cell international, 2020 - Springer
The patients with high microsatellite instability (MSI-H)/mismatch repair deficient (dMMR)
tumors recently have been reported that can benefit from immunotherapy, and MSI can be …

[HTML][HTML] ESMO recommendations on microsatellite instability testing for immunotherapy in cancer, and its relationship with PD-1/PD-L1 expression and tumour …

C Luchini, F Bibeau, MJL Ligtenberg, N Singh… - Annals of …, 2019 - Elsevier
Background Cancers with a defective DNA mismatch repair (dMMR) system contain
thousands of mutations most frequently located in monomorphic microsatellites and are …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer

JD Vogel, SI Felder, AR Bhama… - Diseases of the Colon …, 2022 - journals.lww.com
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …

Detection and localization of surgically resectable cancers with a multi-analyte blood test

JD Cohen, L Li, Y Wang, C Thoburn, B Afsari… - Science, 2018 - science.org
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins …

Early‐onset colorectal cancer in young individuals

G Mauri, A Sartore‐Bianchi, AG Russo… - Molecular …, 2019 - Wiley Online Library
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

Endoscopic recognition and management strategies for malignant colorectal polyps: recommendations of the US Multi-Society Task Force on Colorectal Cancer

A Shaukat, T Kaltenbach, JA Dominitz… - Official journal of the …, 2020 - journals.lww.com
Colorectal polyps are the precursors for most colorectal cancers (CRCs). Some colorectal
polyps accumulate enough mutations to develop high-grade dysplasia and eventual …

[HTML][HTML] Colon cancer: a clinician's perspective in 2019

M Ahmed - Gastroenterology research, 2020 - ncbi.nlm.nih.gov
Colon cancer is a common preventable cancer. With the adoption of widespread colon
cancer screening in the developed countries, the incidence and mortality of colon cancer …

Interplay between MAPK/ERK signaling pathway and MicroRNAs: A crucial mechanism regulating cancer cell metabolism and tumor progression

ER Asl, M Amini, S Najafi, B Mansoori, A Mokhtarzadeh… - Life sciences, 2021 - Elsevier
Mitogen-activated protein kinase (MAPK) signal transduction, as a highly conserved
signaling pathway, is reported to be involved in various biological events, including …

[HTML][HTML] 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation

M Pisano, L Zorcolo, C Merli, S Cimbanassi… - World journal of …, 2018 - Springer
Obstruction and perforation due to colorectal cancer represent challenging matters in terms
of diagnosis, life-saving strategies, obstruction resolution and oncologic challenge. The aims …

[HTML][HTML] Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy

M Yamada, Y Saito, H Imaoka, M Saiko, S Yamada… - Scientific reports, 2019 - nature.com
Gaps in colonoscopy skills among endoscopists, primarily due to experience, have been
identified, and solutions are critically needed. Hence, the development of a real-time robust …