In the 1950s and 1960s, it became apparent that elevated concentrations of plasma
cholesterol were a major risk factor for the development of coronary heart disease, which led …

Background: Increasing evidence suggests a continuous relationship between blood
glucose concentrations and cardiovascular risk, even below diagnostic threshold levels for …

Background The first and second EUROASPIRE surveys showed high rates of modifiable
cardiovascular risk factors in patients with coronary heart disease. The third EUROASPIRE …

Atherosclerotic cardiovascular diseases (CVDs) are the biggest causes of death worldwide.
In most people, CVD is the product of a number of causal risk factors. Several seemingly …

Statins (HMG-CoA reductase inhibitors) are used widely for the treatment of
hypercholesterolemia. They inhibit HMG-CoA reductase competitively, reduce LDL levels …

Since the first Joint European Societies (European Society of Cardiology, European
Atherosclerosis Society and European Society of Hypertension) Task Force …

Scientific advances in this field have not only given us a better understanding of what is an
optimal diet, but has allowed food and nutraceutical companies to market products with …

ContextThe Framingham Heart Study helped to establish tools to assess coronary heart
disease (CHD) risk, but the homogeneous nature of the Framingham population prevents …

Abstract Background European Action on Secondary and Primary Prevention by Intervention
to Reduce Events (EUROASPIRE) IV in primary care was a cross-sectional survey carried …

Background Children generally have low cholesterol and no clinical manifestations of
atherosclerosis, but fatty-streak formation begins in fetuses and is greatly increased by …