Mounting evidence progressively appreciates the vital interplay between immunity and
metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and …

Ischemic stroke, a disease with high mortality and disability rate worldwide, currently has no
effective treatment. The systemic inflammation response to the ischemic stroke, followed by …

Ischemic stroke (IS) is a fatal neurological disease that occurs when the blood flow to the
brain is disrupted, leading to brain tissue damage and functional impairment. Cellular …

Introduction A crucial aspect of stroke progression is the inflammatory response. As novel
inflammatory and prognostic markers, the systemic immune inflammation index (SII) and the …

Background Spinal cord injury (SCI), which causes loss of sensory and motor function in the
body below the level of injury, is a devastating disease of the central nervous system. SCI …

Stroke is the second leading cause of death worldwide, and hypoxia is a major crisis of the
brain after stroke. Therefore, providing oxygen to the brain microenvironment can effectively …

Ischemic stroke (IS), which is the third foremost cause of disability and death worldwide, has
inflammation and cell death as its main pathological features. IS can lead to neuronal cell …

Cerebral ischemia reperfusion (I/R) is one of the neurovascular diseases which leads to
severe brain deterioration. Haemorrhagic transformation (HT) is the main complication of …

Precise and efficient regulation of microglia is vital for ischemic stroke therapy and
prognosis. The infiltration of neutrophils into the brain provides opportunities for regulatory …

Background and Purpose Immune and inflammatory response plays a central role in the
clinical outcomes of stroke. This study is aimed to explore the clinical significance of the new …