Irisin/PGC-1α/FNDC5 pathway in Parkinson's disease: truth under the throes

NH Ali, NA Alhamdan, HM Al-Kuraishy… - Naunyn-Schmiedeberg's …, 2024 - Springer
Parkinson's disease (PD) is considered one of the most common neurodegenerative brain
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …

The probable role of tissue plasminogen activator/neuroserpin axis in Alzheimer's disease: a new perspective

NH Ali, HM Al-Kuraishy, AI Al-Gareeb… - Acta Neurologica …, 2024 - Springer
Alzheimer's disease (AD) is the most common type of dementia associated with amyloid
beta (Aβ) deposition. Dysfunction of the neuronal clearance pathway promotes the …

Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury

VV Andrianov, VA Kulchitsky, GG Yafarova, LV Bazan… - Molecules, 2023 - mdpi.com
Nitric oxide (NO) production in injured and intact brain regions was compared by EPR
spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of …

Correlation analysis of inflammatory markers with the short-term prognosis of acute ischaemic stroke

F Zhu, Z Wang, J Song, Y Ji - Scientific Reports, 2024 - nature.com
Stroke is the second leading cause of death worldwide, and China has the highest stroke
incidence in the world. The systemic inflammatory response index (SIRI), systemic …

Targeting neuron-non-neuronal interactions at the neurovascular unit in stroke and neurodegenerative disease models

C Li, Y Liu, J Liu, X Xu - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Stroke and neurodegenerative diseases continue to be major global contributors to mortality
and disability (Pak et al., 2023; Walker et al., 2023). Regrettably, current treatment fall short …

The lncRNA lnc_AABR07044470. 1 promotes the mitochondrial-damaged inflammatory response to neuronal injury via miR-214-3p/PERM1 axis in acute ischemic …

M Wang, H Li, Y Qian, S Zhao, H Wang, Y Wang… - Molecular Biology …, 2024 - Springer
Purpose We investigated the role of lnc_AABR07044470. 1 on the occurrence and
development of acute ischemic stroke (AIS) and neuronal injury by targeting the miR-214 …

An EPR Spectroscopy Study of NO and Copper Content in Injured and Uninjured Areas of the Brain After a Combined Injury of the Brain and Spinal Cord in Rats

VV Andrianov, VA Kulchitsky, GG Yafarova, LV Bazan… - 2023 - preprints.org
Here we performed a comparative experimental analysis by EPR spectroscopy of the
intensity of nitric oxide (NO) production and copper content in the injured and uninjured …

Correlation analysis of the SIRI, PLR and NLR with the short-term prognosis of acute cerebral infarction

F Zhu, Z Wang, J Song, Y Ji - 2024 - researchsquare.com
Stroke is the second leading cause of death worldwide. The incidence of stroke in China is
the highest in the world. Numerous studies have confirmed the clinical value of the SIRI, SII …