Palliative sedation in end-of-life care and survival: a systematic review

M Maltoni, E Scarpi, M Rosati, S Derni… - Journal of clinical …, 2012 - ascopubs.org
Purpose Palliative sedation is a clinical procedure aimed at relieving refractory symptoms in
patients with advanced cancer. It has been suggested that sedative drugs may shorten life …

Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards

AD Graeff, M Dean - Journal of palliative medicine, 2007 - liebertpub.com
Purpose: Palliative sedation therapy (PST) is a controversial issue. There is a need for
internationally accepted definitions and standards. Methods: A systematic review of the …

European Association for Palliative Care (EAPC) recommended framework for the use of sedation in palliative care

NI Cherny, L Radbruch… - Palliative …, 2009 - journals.sagepub.com
The European Association for Palliative Care (EAPC) considers sedation to be an important
and necessary therapy in the care of selected palliative care patients with otherwise …

ESMO Clinical Practice Guidelines for the management of refractory symptoms at the end of life and the use of palliative sedation

NI Cherny - Annals of oncology, 2014 - annalsofoncology.org
In patients with advanced cancer, a readiness to address pain and other intolerable
symptoms is a medical and moral imperative [1]. This has been described by Roy as the …

The use of opioids and sedatives at the end of life

N Sykes, A Thorns - The lancet oncology, 2003 - thelancet.com
Opioids and sedative drugs are commonly used to control symptoms in patients with
advanced cancer. However, it is often assumed that the use of these drugs inevitably results …

Palliative options of last resort: a comparison of voluntarily stopping eating and drinking, terminal sedation, physician-assisted suicide, and voluntary active euthanasia

TE Quill, B Lo, B Lo, DW Brock - Jama, 1997 - jamanetwork.com
Palliative care is generally agreed to be the standard of care for the dying, but there remain
some patients for whom intolerable suffering persists. In the face of ethical and legal …

The role of chemotherapy at the end of life:“when is enough, enough?”

SE Harrington, TJ Smith - Jama, 2008 - jamanetwork.com
Patients face difficult decisions about chemotherapy near the end of life. Such treatment
might prolong survival or reduce symptoms but cause adverse effects, prevent the patient …

[HTML][HTML] Palliative sedation: a review of the research literature

P Claessens, J Menten, P Schotsmans… - Journal of pain and …, 2008 - Elsevier
The overall aim of this paper is to systematically review the following important aspects of
palliative sedation: prevalence, indications, survival, medication, food and fluid intake …

[HTML][HTML] Palliative sedation therapy does not hasten death: results from a prospective multicenter study

M Maltoni, C Pittureri, E Scarpi, L Piccinini, F Martini… - Annals of …, 2009 - Elsevier
Background: Palliative sedation therapy (PST) is indicated for and used to control refractory
symptoms in cancer patients undergoing palliative care. We aimed to evaluate whether PST …

The rule of double effect—a critique of its role in end-of-life decision making

TE Quill, R Dresser, DW Brock - New England Journal of …, 1997 - Mass Medical Soc
According to the ethical principle known as the “rule of double effect,” effects that would be
morally wrong if caused intentionally are permissible if foreseen but unintended. This …