[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
Oral drug delivery platforms for biomedical applications
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
Nanoemulsion: Concepts, development and applications in drug delivery
Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …
[HTML][HTML] Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of …
Conventional oral therapy of lymphatic filariasis drugs is only effective to kill microfilariae in
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …
[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
[HTML][HTML] Intervertebral disc degeneration—Current therapeutic options and challenges
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …
declining function and the development of pain, it may affect one's physical health, mental …
[HTML][HTML] Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …
among women and the lack of expressed receptors has made treatment options …
[HTML][HTML] Organ-on-a-chip platforms for accelerating the evaluation of nanomedicine
Nanomedicine involves the use of engineered nanoscale materials in an extensive range of
diagnostic and therapeutic applications and can be applied to the treatment of many …
diagnostic and therapeutic applications and can be applied to the treatment of many …
Bile acid transporter-mediated oral drug delivery
Bile acids are synthesized in the liver, stored in the gallbladder, and secreted into the
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …