[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Nanoemulsion: Concepts, development and applications in drug delivery

Y Singh, JG Meher, K Raval, FA Khan… - Journal of controlled …, 2017 - Elsevier
Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …

Nanoparticles for oral delivery: Design, evaluation and state-of-the-art

AA Date, J Hanes, LM Ensign - Journal of Controlled Release, 2016 - Elsevier
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

[HTML][HTML] Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of …

AD Permana, IA Tekko, MTC McCrudden… - Journal of controlled …, 2019 - Elsevier
Conventional oral therapy of lymphatic filariasis drugs is only effective to kill microfilariae in
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …

[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers

CH Lin, CH Chen, ZC Lin, JY Fang - Journal of food and drug analysis, 2017 - Elsevier
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

[HTML][HTML] Intervertebral disc degeneration—Current therapeutic options and challenges

A Samanta, T Lufkin, P Kraus - Frontiers in Public Health, 2023 - frontiersin.org
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …

[HTML][HTML] Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy

A Chaudhuri, DN Kumar, RA Shaik, BG Eid… - International journal of …, 2022 - mdpi.com
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …

[HTML][HTML] Organ-on-a-chip platforms for accelerating the evaluation of nanomedicine

X Chen, YS Zhang, X Zhang, C Liu - Bioactive Materials, 2021 - Elsevier
Nanomedicine involves the use of engineered nanoscale materials in an extensive range of
diagnostic and therapeutic applications and can be applied to the treatment of many …

Bile acid transporter-mediated oral drug delivery

F Deng, YH Bae - Journal of Controlled Release, 2020 - Elsevier
Bile acids are synthesized in the liver, stored in the gallbladder, and secreted into the
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …