A triple-signal amplification strategy was proposed for highly sensitive and selective
detection of thymine DNA glycosylase (TDG) by coupling a dendrimer-like DNA label with …

A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase
activity based on exonuclease-mediated amplification - Chemical Communications (RSC …

The mammalian thymine DNA glycosylase (TDG) excises 5-carboxylcytosine (5caC) when
paired with a guanine in a CpG sequence, in addition to mismatched bases. Here we …

Inhibition of protein kinase C (PKC) efficiently promoted the self-renewal of embryonic stem
cells (ESCs). However, information about the function of PKC inhibition remains lacking …

Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in
studies of DNA replication in living cells and in DNA functionalization for bionanotechology …

Formylcytosine (5fC) is a chemically edited, naturally occurring nucleobase which appears
in the context of modified DNA strands. The understanding of the impact of 5fC on dsDNA …

Arabidopsis thaliana repressor of silencing 1 (ROS1) is a multi-domain bifunctional DNA
glycosylase/lyase, which excises 5-methylcytosine (5mC) and 5-hydroxymethylcytosine …

In Caenorhabditis elegans, two DNA glycosylases, UNG-1 and NTH-1, and two AP
endonucleases, APN-1 and EXO-3, have been characterized from the base-excision repair …

Methylcytosine is one of the most important epigenetic modifications and has a profound
impact on embryonic development. After gamete fusion, there is a widespread and rapid …

Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the
FANC genes. FA cells are mainly characterized by extreme hypersensitivity to interstrand …