A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

ToxIBTL: prediction of peptide toxicity based on information bottleneck and transfer learning

L Wei, X Ye, T Sakurai, Z Mu, L Wei - Bioinformatics, 2022 - academic.oup.com
Motivation Recently, peptides have emerged as a promising class of pharmaceuticals for
various diseases treatment poised between traditional small molecule drugs and therapeutic …

Strategies and progresses for enhancing targeted antibiotic delivery

A Nazli, DL He, D Liao, MZI Khan, C Huang… - Advanced drug delivery …, 2022 - Elsevier
Antibiotic resistance is a global health issue and a potential risk for society. Antibiotics
administered through conventional formulations are devoid of targeting effect and often …

Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

ATSE: a peptide toxicity predictor by exploiting structural and evolutionary information based on graph neural network and attention mechanism

L Wei, X Ye, Y Xue, T Sakurai… - Briefings in Bioinformatics, 2021 - academic.oup.com
Motivation: Peptides have recently emerged as promising therapeutic agents against
various diseases. For both research and safety regulation purposes, it is of high importance …

Anti-cancer peptides: Their current trends in the development of peptide-based therapy and anti-tumor drugs

A Lath, AR Santal, N Kaur, P Kumari… - Biotechnology and …, 2023 - Taylor & Francis
Human cancer remains a cause of high mortality throughout the world. The conventional
methods and therapies currently employed for treatment are followed by moderate-to-severe …

1, 2, 3-Triazoles as biomimetics in peptide science

N Agouram, EM El Hadrami, A Bentama - Molecules, 2021 - mdpi.com
Natural peptides are an important class of chemical mediators, essential for most vital
processes. What limits the potential of the use of peptides as drugs is their low bioavailability …

[HTML][HTML] Bioactive peptides for boosting stem cell culture platform: Methods and applications

AA Dayem, SB Lee, KM Lim, A Kim, HJ Shin… - Biomedicine & …, 2023 - Elsevier
Peptides, short protein fragments, can emulate the functions of their full-length native
counterparts. Peptides are considered potent recombinant protein alternatives due to their …

Bioactive natural products from Bacteroidetes

S Brinkmann, MS Spohn, TF Schäberle - Natural product reports, 2022 - pubs.rsc.org
Covering: up to end of January 2022 Bacteria representing the phylum Bacteroidetes
produce a diverse range of natural products, including polyketides, peptides and lactams …