Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis

M Thakur, Y Kumar, V Yadav, A Pramanik… - Biochemical …, 2023 - Elsevier
Pseudomonas aeruginosa can utilize various virulence factors necessary for host infection
and persistence. These virulence factors include pyocyanin, proteases, exotoxins, 2-heptyl-4 …

Current and Emerging Inhaled Antibiotics for Chronic Pulmonary Pseudomonas aeruginosa and Staphylococcus aureus Infections in Cystic Fibrosis

D Li, EK Schneider-Futschik - Antibiotics, 2023 - mdpi.com
Characterized by impaired mucus transport and subsequent enhanced colonization of
bacteria, pulmonary infection causes major morbidity and mortality in patients with cystic …

Antibiotic resistance in chronic respiratory diseases: from susceptibility testing to the resistome

H Pailhoriès, JL Herrmann… - European …, 2022 - Eur Respiratory Soc
The development of resistome analysis, ie the comprehensive analysis of antibiotic-
resistance genes (ARGs), is enabling a better understanding of the mechanisms of antibiotic …

Inhaled antibiotics: A promising drug delivery strategies for efficient treatment of lower respiratory tract infections (LRTIs) associated with antibiotic resistant biofilm …

N Islam, D Reid - Respiratory Medicine, 2024 - Elsevier
Antibiotic-resistant bacteria associated with LRTIs are frequently associated with inefficient
treatment outcomes. Antibiotic-resistant Streptococcus pneumoniae, Haemophilus …

[Retracted] Clinical Efficacy and Safety Analysis of Levofloxacin for the Prevention of Infection after Traumatic Osteoarthrosis and Internal Fixation: Systematic Review …

W Wang, CQ Zou, J Zhang - Emergency Medicine International, 2022 - Wiley Online Library
Objective. Levofloxacin has been widely used in clinical anti‐infection treatment; however,
its adverse reactions to levofloxacin were also obvious in patients. Herein we aimed to …

[HTML][HTML] Inhaled antimicrobial prescribing for Pseudomonas aeruginosa infections in Europe

CM Sloan, LJ Sherrard, GG Einarsson, LJ Dupont… - Journal of Cystic …, 2024 - Elsevier
Background Prescribers have an increasing range of inhaled antimicrobial formulations to
choose from when prescribing both eradication and chronic suppression regimens in cystic …

Differential performance and lung deposition of levofloxacin with different nebulisers used in cystic fibrosis

C Schwarz, C Procaccianti, L Costa, R Brini… - International Journal of …, 2022 - mdpi.com
We compared the performance and levofloxacin (Quinsair) lung deposition of three
nebulisers commonly used in CF (I-Neb Advance, eFlow rapid, and LC Plus) with the …

Inhalatorni antibiotici i indikacije za njihovu primjenu

P Bolković - 2023 - repozitorij.mef.unizg.hr
Inhalatorni su se antibiotici počeli primjenjivati 40-ih godina 20. stoljeća za liječenje
kroničnih infekcija dišnog sustava, najprije kao aerosolizirani oblici antibiotika namijenjenih …

Recent Developments in the Treatment of Bacterial Pneumonia

G Johnson, M Young, J Gordon, C Preuss - Infectious Diseases Drug …, 2023 - Springer
Bacterial pneumonia acquired from either the community, hospital, ventilators, aspiration, or
tuberculous organisms represents a threat to an immunocompromised host as much as a …

[PDF][PDF] Co-amorphous spray-dried microparticles for pulmonary drug delivery to treat lung infections

BR Adhikari - 2022 - ourarchive.otago.ac.nz
Background: Spray drying is a common technique to produce inhalable high-dose dry
powder for treating lung infections. However, the particles produced by the technique …