Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy associated with
high-risk human papillomavirus (HPV) and is currently one of the fastest-growing causes of …

Squamous cell carcinoma of the anal canal (SCCA) is a rare neoplasm, but with rising
incidence rates in the past few decades; it is etiologically linked with the human …

For decades, chemoradiotherapy for early-stage disease and systemic chemotherapy for
advanced disease have represented the mainstay of treatment for anal cancer. Over the last …

Anal squamous cell carcinoma (SCAC) is a human papillomavirus (HPV) driven malignancy.
Given inadequate HPV-vaccination rates, SCAC will continue to be a public health concern …

Squamous Cell Carcinoma of the Anal canal (SCCA) is a rare disease associated with a
Human Papillomavirus (HPV) infection in most cases, predominantly the HPV16 genotype …

Background Chemoradiation therapy (CRT) is the standard of care for squamous cell
carcinoma of the anus (SCCA), the most common type of anal cancer. However …

Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy linked 26 to
high-risk Human papillomavirus (HPV) infection, which develops from 27 precursor lesions …

Abstract Purpose of Review We aim to summarise the available evidence on systemic
therapies for advanced anal cancer. Recent Findings There is no universal consensus on …

Simple Summary Anal cancer is rare with an estimated 9000 new cases predicted to occur
in the United States in 2021. However, rates of new anal cancer cases and deaths from the …

Anal squamous cell carcinoma (ASCC) is a rare tumour, but its incidence is increasing.
Standard chemoradiotherapy fails to cure 20% of patients and no targeted therapy is …