Objectives Metastatic squamous cell carcinoma anal cancer (SCCA) is rare. Prospective
data recommends front-line platinum doublet combinations and second-line anti …

Anal cancer is a rare malignancy for which cisplatin with 5-fluorouracil is the recommended
treatment for patients with metastatic disease. Because most cases of anal cancer are linked …

Introduction Anal cancer is a rare malignancy with increasing incidence, notably in women.
This disease is highly associated with HPV infection and its incidence and mortality are …

Genomic alterations of anal squamous cell carcinoma (ASCC) remain poorly understood
due to the rarity of this tumor. Array comparative genomic hybridization and targeted gene …

Abstract Purpose of Review Standard treatment for early-stage squamous cell cancer of the
anal canal (SCCA) includes concurrent chemotherapy and radiation to achieve curative …

Simple Summary Our review summarizes the experience of eight hepatic-only metastatic
squamous cell carcinoma of the anal canal cases who underwent hepatic resection …

Background Hypoxia-inducible factor-1α (HIF-1α) is a crucial transcription factor activated
under hypoxic conditions, known to regulate genes associated with tumor survival …

While immune checkpoint inhibitors (ICI) have shown clear signal in patients with
esophageal cancer (EC), they only benefit for a subset of patient and the fast majority of …

Background Anal canal squamous cell carcinoma (ACSCC) is an exceedingly rare
malignant neoplasm with challenges in sphincter preservation, treatment toxicities and long …

Introduction: Squamous cell carcinoma of the anal canal (SCCA) is a rare malignancy, but its
incidence rates have been increasing in the last decade. Studies have demonstrated that up …