Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Introduction Cerebral autoregulation (CA) is a theoretical construct characterized by the
relationship between mean arterial pressure (MAP) and cerebral blood flow (CBF). We …

Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …

Background and Purpose—Cerebral autoregulation may be impaired in the early days after
subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship …

Cerebral autoregulation refers to the mechanisms that act to keep cerebral blood flow (CBF)
constant during changes in blood pressure. The mechanisms of cerebral autoregulation …

New Findings What is the topic of this review? Cerebrovascular reactivity to CO2, which is a
principal factor in determining ventilatory responses to CO2 through the role reactivity plays …

The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained
increased interest. The CPA is often disturbed as a consequence of acute brain injury, which …

Transcranial Doppler (TCD) is a rapid and non-invasive diagnostic technique that can
provide real-time measurements of the relative changes in cerebral blood velocity (CBV) …

Cerebrovascular reactivity can be measured as the cerebrovascular flow response to a
hypercapnic challenge. The many faceted responses of cerebral blood flow to combinations …

The cerebral vascular network regulates blood flow distribution by adjusting vessel
diameters, and consequently resistance to flow, in response to metabolic demands …