Aims To analyse the safety and efficacy of direct oral anticoagulants (DOACs) in real-world
studies including atrial fibrillation (AF) patients. Methods and results Systematic review and …

Background The introduction of direct oral anticoagulants (DOAC) has resulted in a
paradigm shift in the management of venous thromboembolism (VTE). We evaluate the …

Direct oral anticoagulant drugs (DOACs) interfere with the coagulation process, thus
improving patient care for those who require anticoagulant treatment. This study presents a …

Abstract Backgound Atrial Fibrillation (AF) is the most prevalent cardiac arrhythmia among
older patients, associated with thromboembolic events. Direct Oral Anticoagulants (DOAC) …

Background: Non-vitamin K antagonist oral anticoagulants (NOACs) are more commonly
used to prevent atrial fibrillation (AF) patients from thromboembolic events than vitamin K …

The optimal management of oral anticoagulation (OAC) in the acute phase of non valvular
atrial fibrillation (NVAF)-related acute ischemic stroke (AIS) remains controversial, especially …

Objective. We aimed to further investigate the efficacy and safety of low‐dose NOACs by
performing a meta‐analysis of cohort studies. Background. Meta‐analyses of randomized …

Background The prevalence of atrial fibrillation (AF) increases with age. The prescription of
anticoagulation in very elderly patients is controversial and sometimes underused. Our …

Abstract Purpose of Review In this narrative review, we focus on aspects of the complicated
relationship between frailty and medications that we feel would be of particular interest to …

The prevalence of atrial fibrillation (AF) increases with age, as does the proportion of
patients with frailty. AF patients with frailty have a higher risk of stroke than those without …