Parkinson disease (PD) is the second most common neurodegenerative disorder, affecting>
1% of the population≥ 65 years of age and with a prevalence set to double by 2030. In …

Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

MR-guided focused ultrasound (MRgFUS), in combination with intravenous microbubble
administration, has been applied for focal temporary BBB opening in patients with …

Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

Abstract Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD), which share many clinical, neurochemical, and morphological features, have been …

Lewy body diseases share clinical, pathological, genetic and biochemical signatures, and
are regarded as a highly heterogeneous group of neurodegenerative disorders. Inclusive of …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

The current nosological concept of α-synucleinopathies characterized by the presence of
Lewy bodies (LBs) includes Parkinson's disease (PD), Parkinson's disease dementia (PDD) …

Synucleinopathies such as Parkinson's disease (PD) are hallmarked by α‐synuclein (α‐syn)
pathology and neuroinflammation. This neuroinflammation involves activated microglia with …

Dementia, a chronic and progressive cognitive declination of brain function caused by
disease or impairment, is becoming more prevalent due to the aging population. A major …