MiR-199-3p replacement affects E-cadherin expression through Notch1 targeting in hepatocellular carcinoma
C Giovannini, F Fornari, R Dallo, M Gagliardi, E Nipoti… - Acta histochemica, 2018 - Elsevier
Hepatocellular carcinoma (HCC) represents the second cause of cancer-related mortality
worldwide and is associated with poor prognosis, due to a high recurrence rate after curative …
worldwide and is associated with poor prognosis, due to a high recurrence rate after curative …
Experimental drug treatments for hepatocellular carcinoma: clinical trial failures 2015 to 2021
Introduction Hepatocellular carcinoma (HCC) is a major health problem worldwide with
limited systemic therapy options. Since the approval of sorafenib in 2008, no systemic …
limited systemic therapy options. Since the approval of sorafenib in 2008, no systemic …
[HTML][HTML] Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures
S Golriz Khatami, S Mubeen, VS Bharadhwaj… - npj Systems Biology …, 2021 - nature.com
The utility of pathway signatures lies in their capability to determine whether a specific
pathway or biological process is dysregulated in a given patient. These signatures have …
pathway or biological process is dysregulated in a given patient. These signatures have …
[HTML][HTML] FGF8 promotes cell proliferation and resistance to EGFR inhibitors via upregulation of EGFR in human hepatocellular carcinoma cells
Y Pei, X Sun, X Guo, H Yin, L Wang… - Oncology …, 2017 - spandidos-publications.com
Abstract Fibroblast growth factor 8 (FGF8), a member of the fibroblast growth factor (FGF)
family, is upregulated in several human cancers, including HCC (HCC). Previous studies …
family, is upregulated in several human cancers, including HCC (HCC). Previous studies …
[HTML][HTML] Insights into growth factors in liver carcinogenesis and regeneration: An ongoing debate on minimizing cancer recurrence after liver resection
AI Álvarez-Mercado, A Caballeria-Casals… - Biomedicines, 2021 - mdpi.com
Hepatocellular carcinoma has become a leading cause of cancer-associated mortality
throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the …
throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the …
Research progress in targeted therapy of hepatocellular carcinoma
Q Chen, X Yang - Chinese Medical Sciences Journal, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common malignancies, and its treatment
is limited. With the understanding of key genes and signaling pathways in the occurrence …
is limited. With the understanding of key genes and signaling pathways in the occurrence …
[HTML][HTML] Potential molecular targeted therapy for unresectable hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers,
representing a serious worldwide health concern. The recurrence incidence of …
representing a serious worldwide health concern. The recurrence incidence of …
Titanium oxide nanoparticles improve the chemotherapeutic action of erlotinib in liver cancer cells
SE Abdel-Ghany, E El-Sayed, N Ashraf… - Current Cancer …, 2020 - ingentaconnect.com
Background: Hepatocellular carcinoma is the second leading cause of cancer-related
deaths among other types of cancer due to lack of effective treatments and late diagnosis …
deaths among other types of cancer due to lack of effective treatments and late diagnosis …
Comprehensive analysis of the role of pyroptosis-related genes in predicting prognosis in hepatocellular carcinoma
L Tian, J He, R Yang, J Zhou - 2023 - researchsquare.com
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies
worldwide. Pyroptosis is an inflammatory form of programmed cell death closely related to …
worldwide. Pyroptosis is an inflammatory form of programmed cell death closely related to …