cGMP regulated protein kinases (cGK)
F Hofmann, D Bernhard, R Lukowski… - … generators, effectors and …, 2009 - Springer
Abstract cGMP-dependent protein kinases (cGK) are serine/threonine kinases that are
widely distributed in eukaryotes. Two genes—prkg1 and prkg2—code for cGKs, namely …
widely distributed in eukaryotes. Two genes—prkg1 and prkg2—code for cGKs, namely …
cGMP-dependent protein kinases (cGK)
F Hofmann, JW Wegener - Guanylate Cyclase and Cyclic GMP: Methods …, 2013 - Springer
Abstract cGMP-dependent protein kinases (cGK) are serine/threonine kinases that are
widely distributed in eukaryotes. Two genes—prkg1 and prkg2—code for cGKs, namely …
widely distributed in eukaryotes. Two genes—prkg1 and prkg2—code for cGKs, namely …
[HTML][HTML] Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage
PJ Fanning, G Emkey, RJ Smith, AJ Grodzinsky… - Journal of biological …, 2003 - ASBMB
Articular chondrocytes respond to mechanical forces by alterations in gene expression,
proliferative status, and metabolic functions. Little is known concerning the cell signaling …
proliferative status, and metabolic functions. Little is known concerning the cell signaling …
[PDF][PDF] Insights into cGMP signalling derived from cGMP kinase knockout mice
J Schlossmann, R Feil, F Hofmann - Front Biosci, 2005 - researchgate.net
Cyclic GMP 3. cGKs: genes and proteins 3.1. cGKI and cGKII in mammals 3.2. cGK
signalling 3.3. cGK knockout mice 4. cGK: function 4.1. cGKI in the cardiovascular system …
signalling 3.3. cGK knockout mice 4. cGK: function 4.1. cGKI in the cardiovascular system …
Cbfa-1 mediates nitric oxide regulation of MMP-13 in osteoblasts
C Zaragoza, E López-Rivera… - Journal of cell …, 2006 - journals.biologists.com
During bone development, osteoblast differentiation requires remodeling of the extracellular
matrix. Although underlying mechanisms have not been elucidated, evidence points to the …
matrix. Although underlying mechanisms have not been elucidated, evidence points to the …
[HTML][HTML] More knee joint osteoarthritis (OA) in mice after inactivation of one allele of type II procollagen gene but less OA after lifelong voluntary wheel running exercise
T Lapveteläinen, M Hyttinen, J Lindblom… - Osteoarthritis and …, 2001 - Elsevier
Objective To investigate the incidence and severity of osteoarthritis (OA) and the effects of
voluntary wheel running in normal mice and mice carrying either a targeted inactivation of …
voluntary wheel running in normal mice and mice carrying either a targeted inactivation of …
The novel gene locus for agenesis of permanent teeth (He-Zhao deficiency) maps to chromosome 10q11. 2
W Liu, H Wang, S Zhao, W Zhao, S Bai… - Journal of dental …, 2001 - journals.sagepub.com
He-Zhao deficiency has been recently characterized with a distinct form of agenesis of
permanent teeth that is different from other previously reported disorders of tooth agenesis …
permanent teeth that is different from other previously reported disorders of tooth agenesis …
Collagens: building blocks at the end of the development line
PH Byers - Clinical genetics, 2000 - Wiley Online Library
Collagens are some of the majr building blocks of the vertebrate body. In addition to their
structural role, they are important for cell guidance during development and for maintaining …
structural role, they are important for cell guidance during development and for maintaining …
[HTML][HTML] Regionalization, constraints, and the ancestral ossification patterns in the vertebral column of amniotes
A Verrière, NB Fröbisch, J Fröbisch - Scientific Reports, 2022 - nature.com
The development of the vertebral column has been studied extensively in modern amniotes,
yet many aspects of its evolutionary history remain enigmatic. Here we expand the existing …
yet many aspects of its evolutionary history remain enigmatic. Here we expand the existing …
Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice
T Lapveteläinen, MM Hyttinen… - Annals of the …, 2002 - ard.bmj.com
Objectives: To investigate the effects of voluntary running on the incidence and severity of
osteoarthritis (OA) and associated changes in cartilage matrix and subchondral bone in a …
osteoarthritis (OA) and associated changes in cartilage matrix and subchondral bone in a …