Cerebral small vessel disease: a review of the pathophysiological mechanisms

Y Hannawi - Translational Stroke Research, 2023 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

Insights into the pathological basis of dementia from population‐based neuropathology studies

SB Wharton, JE Simpson, PG Ince… - Neuropathology and …, 2023 - Wiley Online Library
The epidemiological neuropathology perspective of population and community‐based
studies allows unbiased assessment of the prevalence of various pathologies and their …

Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment

KE Askew, J Beverley, E Sigfridsson, S Szymkowiak… - Glia, 2024 - Wiley Online Library
White matter abnormalities, related to poor cerebral perfusion, are a core feature of small
vessel cerebrovascular disease, and critical determinants of vascular cognitive impairment …

Meta‐analysis of association between migraine and risk of dementia

L Wang, JC Wu, FY Wang, X Chen… - Acta Neurologica …, 2022 - Wiley Online Library
Objectives The association between migraine and dementia has rarely been investigated,
and available results are conflicting. Thus, the aim of this meta‐analysis was to evaluate …

[HTML][HTML] Exosomal miRNA-223-3p as potential biomarkers in patients with cerebral small vessel disease cognitive impairment

W Zhao, W Sun, S Li, Y Jiao, Z Wang, T Wu… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Cerebrovascular disease is a common clinical illness. Many patients with
cerebrovascular disease can be accompanied by cognitive impairment. The exosomal …

Retinotectal plasticity induced by monocular enucleation during the critical period is dependent of A2a adenosine receptor: a possible role of astrocytes

AL Tavares-Gomes, B Teixeira-Silva… - Experimental …, 2023 - Elsevier
The retinotectal topography of rats develops within the first three postnatal weeks during the
critical period. Previous studies have shown that monocular enucleation results in plasticity …

Microvessel stenosis, enlarged perivascular spaces, and fibrinogen deposition are associated with ischemic periventricular white matter hyperintensities

AD Roseborough, B Rasheed, Y Jung… - Brain …, 2022 - Wiley Online Library
Periventricular white matter hyperintensities (pvWMH) are neuroimaging abnormalities
surrounding the lateral ventricles that are apparent on magnetic resonance imaging (MRI) …

Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke

Y Hase, KE Ameen‐Ali, R Waller, JE Simpson… - Brain …, 2022 - Wiley Online Library
With the hypothesis that perivascular microglia are involved as neuroinflammatory
components of the gliovascular unit contributing to white matter hyperintensities on MRI and …

The Impact of Dipyridamole on Disease-Associated Microglia Phenotypic Transformation in White Matter Lesions Induced by Chronic Cerebral Hypoperfusion

W Cheng, Y Wang, L Zhang, C Cheng, X Chen… - Neurochemical …, 2024 - Springer
White matter lesions (WMLs) resulting from chronic cerebral hypoperfusion (CCH) are the
leading cause of vascular dementia (VaD). This study aimed to investigate whether …

The Impact of Atmospheric Cadmium Exposure on Colon Cancer and the Invasiveness of Intestinal Stents in the Cancerous Colon

S Zhang, R Li, J Xu, Y Liu, Y Zhang - Toxics, 2024 - mdpi.com
Background: Inhalation exposure to carcinogenic metals such as cadmium (Cd) is a
significant global health concern linked to various cancers. However, the precise …