[HTML][HTML] Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and …
Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …
[HTML][HTML] Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies
S Ben-Shabat, L Yarmolinsky, D Porat… - Drug delivery and …, 2020 - Springer
Viral infections affect three to five million patients annually. While commonly used antivirals
often show limited efficacy and serious adverse effects, herbal extracts have been in use for …
often show limited efficacy and serious adverse effects, herbal extracts have been in use for …
Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health
Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of
years, it has helped humans fight diseases and protect life, health, and reproduction …
years, it has helped humans fight diseases and protect life, health, and reproduction …
An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers
Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …
effectiveness, ease of administration, and high patient compliance. However, the absorption …
[HTML][HTML] Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review
M Vertzoni, P Augustijns, M Grimm, M Koziolek… - European journal of …, 2019 - Elsevier
Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …
Predicting a Drug's Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data
BJ Bennion, NA Be, MW McNerney, V Lao… - The journal of …, 2017 - ACS Publications
Membrane permeability is a key property to consider during the drug design process, and
particularly vital when dealing with small molecules that have intracellular targets as their …
particularly vital when dealing with small molecules that have intracellular targets as their …
The biopharmaceutics classification system (BCS) and the biopharmaceutics drug disposition classification system (BDDCS): beyond guidelines
A Charalabidis, M Sfouni, C Bergström… - International journal of …, 2019 - Elsevier
The recent impact of the Biopharmaceutics Classification System (BCS) and the
Biopharmaceutics Drug Disposition Classification System (BDDCS) on relevant scientific …
Biopharmaceutics Drug Disposition Classification System (BDDCS) on relevant scientific …
A well plate–based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature
Owing to their high spatiotemporal precision and adaptability to different host cells, organ-on-
a-chip systems are showing great promise in drug discovery, developmental biology studies …
a-chip systems are showing great promise in drug discovery, developmental biology studies …
Automated experimentation powers data science in chemistry
Y Shi, PL Prieto, T Zepel, S Grunert… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus Data science has revolutionized chemical research and continues to break
down barriers with new interdisciplinary studies. The introduction of computational models …
down barriers with new interdisciplinary studies. The introduction of computational models …
Diffusion and Flux Improvement of Drugs through Complexation
Improving the solubility and permeability of drugs via cocrystallization is an important theme
in crystal engineering with practical applications for the discovery and development of high …
in crystal engineering with practical applications for the discovery and development of high …