Neuroprotective activities of curcumin in Parkinson's disease: a review of the literature

EE Nebrisi - International journal of molecular sciences, 2021 - mdpi.com
Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Curcumin, hormesis and the nervous system

M Concetta Scuto, C Mancuso, B Tomasello… - Nutrients, 2019 - mdpi.com
Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …

Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials

C De Waure, C Bertola, G Baccarini, M Chiavarini… - Pharmaceutics, 2023 - mdpi.com
Although the anticancer role of curcumin has been extensively addressed in preclinical
research, only a few studies were carried out in humans, with conflicting results. The aim of …

Curcumin mitigates AFB1-induced hepatic toxicity by triggering cattle antioxidant and anti-inflammatory pathways: A whole transcriptomic in vitro study

M Pauletto, M Giantin, R Tolosi, I Bassan, A Barbarossa… - Antioxidants, 2020 - mdpi.com
Aflatoxin B1 (AFB1) toxicity in livestock and human beings is a major economic and health
concern. Natural polyphenolic substances with antioxidant properties have proven to be …

Curcumin mitigates neuro-inflammation by modulating microglia polarization through inhibiting TLR4 axis signaling pathway following experimental subarachnoid …

YY Gao, Z Zhuang, Y Lu, T Tao, Y Zhou… - Frontiers in …, 2019 - frontiersin.org
Subarachnoid hemorrhage (SAH) elicits destruction of neuronal cells and neurological
function, which is exacerbated by neuro-inflammation in EBI, and toll-like receptor 4 (TLR4) …

Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses

N Choublier, M Taghi, MC Menet, M Le Gall… - Fluids and Barriers of …, 2022 - Springer
Endothelial cells (ECs) are constantly submitted in vivo to hemodynamical forces derived
from the blood circulation, including shear stress (SS). ECs are able to detect SS and …

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke

X Du, N Amin, L Xu, BOA Botchway, B Zhang… - Frontiers in …, 2023 - frontiersin.org
Ischemic-induced neuronal injury arises due to low oxygen/nutrient levels and an
inflammatory response that exacerbates neuronal loss. NOD-like receptor family pyrin …

Curcumin for the management of periodontal diseases: A review

F Forouzanfar, A Forouzanfar… - Current …, 2020 - ingentaconnect.com
Periodontal disease is one of the most common causes of tooth loss among adults.
Research shows that inflammation is one of the crucial components in the initiation and …

[HTML][HTML] Heme oxygenase 1: A novel oncogene in multiple gynecological cancers

JJ Lu, A Abudukeyoumu, X Zhang, LB Liu… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Abstract Heme oxygenase 1 (HO-1), also known as heat shock protein 32 (HSP32), is a
stress-inducible enzyme. In the past, it was believed to participate in maintaining cell …

The Extraction, Determination, and Bioactivity of Curcumenol: A Comprehensive Review

J Li, Y Sun, G Li, C Cheng, X Sui, Q Wu - Molecules, 2024 - mdpi.com
Curcuma wenyujin is a member of the Curcuma zedoaria (zedoary, Zingiberaceae) family,
which has a long history in traditional Chinese medicine (TCM) due to its abundant …