Indirect evidence suggests the increased production of reactive oxygen species (ROS) in
migraine pathophysiology. In the current study we measured lipid peroxidation product in …

Despite the increasing knowledge regarding pain modulation, the understanding of the
mechanisms behind a complex and pathologic chronic pain condition is still insufficient …

Previously, we showed that activation of the spinal CXCL9, 10/CXCR3 pathway mediated
bone cancer pain (BCP) in rats. However, the cellular mechanism involved is poorly …

The hMSCs have become a promising approach for inflammation treatment in acute phase.
Our previous study has demonstrated that human umbilical cord-MSCs could alleviate the …

The effects of Korean red ginseng extract (KRGE) on autoimmune disorders of the nervous
system are not clear. We investigated whether KRGE has a beneficial effect on acute and …

The potential neuroprotective value of ethyl pyruvate (EP) for the treatment of the striatal
toxicity is largely unknown. We investigated whether EP promotes the survival of striatal …

Cyclin-dependent kinase 5 is a proline-directed serine/threonine kinase and its activity
participates in the regulation of nociceptive signaling. Like binding with the activators (P35 …

Korean red ginseng (KRG) possesses neuroprotective activity. However, the potential
neuroprotective value of KRG for the striatal toxicity is largely unknown. We investigated …

Propofol, an intravenous anesthetic, has been shown to offer superior analgesic effect
clinically. Whether propofol has preventive analgesic property remains unexplored. The …

Parkinson disease is a chronic progressive neurodegenerative disorder with a prevalence
that increases with age. The glycolytic end-product pyruvate, has antioxidant and …