[HTML][HTML] Drug safety and suicidality risk of chronic pain medications

O Syed, P Jancic, AB Fink, NN Knezevic - Pharmaceuticals, 2023 - mdpi.com
Chronic pain is one of the main leading causes of disability in the world at present. A variety
in the symptomatology, intensity and duration of this phenomenon has led to an ever …

[HTML][HTML] The Melanocortin System: a promising target for the development of new antidepressant Drugs

DD Markov, OV Dolotov, IA Grivennikov - International Journal of …, 2023 - mdpi.com
Major depression is one of the most prevalent mental disorders, causing significant human
suffering and socioeconomic loss. Since conventional antidepressants are not sufficiently …

Evidence-based care for suicidality as an ethical and professional imperative: How to decrease suicidal suffering and save lives.

DA Jobes, JE Barnett - American Psychologist, 2024 - psycnet.apa.org
Suicide is a major public and mental health problem in the United States and around the
world. According to recent survey research, there were 16,600,000 American adults and …

[HTML][HTML] Suicidal ideation and electroconvulsive therapy: outcomes in adolescents with major depressive disorder

H Cai, R Du, J Song, Z Wang, X Wang, Y Yu… - The Journal of …, 2023 - journals.lww.com
Objective Few studies on electroconvulsive therapy (ECT) investigate efficacy and safety on
depressive adolescents with strong suicidal ideation. Our study examined adolescents …

Real-world effectiveness of repeated intravenous ketamine infusions for treatment-resistant depression in transitional age youth

N Chisamore, K Danayan… - Journal of …, 2023 - journals.sagepub.com
Background: Ketamine is an emerging treatment for treatment-resistant depression (TRD)
associated with rapid and robust improvements in depressive symptoms and suicidality …

[HTML][HTML] Increasing adiponectin signaling by Sub-Chronic AdipoRon treatment elicits antidepressant-and anxiolytic-like effects independent of changes in …

DA Formolo, TH Lee, J Yu, K Lin, G Chen, GS Kranz… - Biomedicines, 2023 - mdpi.com
(1) Background: Adiponectin is an adipocyte-secreted hormone that has antidepressant-and
anxiolytic-like effects in preclinical studies. Here, we investigated the antidepressant-and …

Association between visual impairment and suicide: A systematic review and metaanalysis

A Palbo, ML Roed Rasmussen… - Acta …, 2024 - Wiley Online Library
Visual impairment severely impacts the life of the patients. In this study, we systematically
reviewed studies on the potential relationship between visual impairment and suicidal …

[HTML][HTML] Diagnosis and management of depression in adolescents

DJ Korczak, C Westwell-Roper, R Sassi - CMAJ, 2023 - Can Med Assoc
• Depression is common among adolescents in Canada and has the potential to negatively
affect longterm function and quality of life; despite this, in most affected adolescents …

[HTML][HTML] Clinical practice guidelines for management of suicidal behaviour

S Sarkhel, V Vijayakumar… - Indian Journal of …, 2023 - journals.lww.com
1. Engagement and Therapeutic Alliance‑This is the most crucial step in risk assessment
because if this step is not successfully negotiated, information derived from the patient may …

[HTML][HTML] Omega-3 Alleviates Behavioral and Molecular changes in a Mouse Model of Stress-Induced Juvenile Depression

T Strekalova, D Radford-Smith, IK Dunstan… - Neurobiology of …, 2024 - Elsevier
Introduction Depression is increasingly diagnosed in adolescence, necessitating specific
prevention and treatment methods. However, there is a lack of animal models mimicking …