Osteoarthritis and its management-Epidemiology, nutritional aspects and environmental factors

A Bortoluzzi, F Furini, CA Scirè - Autoimmunity reviews, 2018 - Elsevier
Osteoarthritis (OA) is the most prevalent chronic rheumatic diseases worldwide, with a
strong impact on individual and population health. OA is a clinically heterogeneous disease …

Recent advances in 3D bioprinting of musculoskeletal tissues

T Potyondy, JA Uquillas, PJ Tebon, B Byambaa… - …, 2021 - iopscience.iop.org
The musculoskeletal system is essential for maintaining posture, protecting organs,
facilitating locomotion, and regulating various cellular and metabolic functions. Injury to this …

Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes

A Savadipour, RJ Nims, N Rashidi… - Proceedings of the …, 2023 - National Acad Sciences
Osteoarthritis is a chronic disease that can be initiated by altered joint loading or injury of the
cartilage. The mechanically sensitive PIEZO ion channels have been shown to transduce …

Understanding articular cartilage injury and potential treatments

J Borrelli Jr, SA Olson, C Godbout… - … of orthopaedic trauma, 2019 - journals.lww.com
The goals of all orthopaedic surgeons treating articular cartilage injuries have been
anatomic reduction and stable fixation of the articular cartilage surface with restoration of …

Expanding the therapeutic potential of Salvia miltiorrhiza: a review of its pharmacological applications in musculoskeletal diseases

Z Ye, Y Liu, J Song, Y Gao, H Fang, Z Hu… - Frontiers in …, 2023 - frontiersin.org
Salvia miltiorrhiz, commonly known as “Danshen” in Chinese medicine, has longstanding
history of application in cardiovascular and cerebrovascular diseases. Renowned for its …

Exercise improves subchondral bone microenvironment through regulating bone-cartilage crosstalk

S Zhang, T Li, Y Feng, K Zhang, J Zou… - Frontiers in …, 2023 - frontiersin.org
Articular cartilage degeneration has been proved to cause a variety of joint diseases, among
which osteoarthritis is the most typical. Osteoarthritis is characterized by articular cartilage …

Transient receptor potential ankyrin 1 (trpa1) mediates il-1β-induced apoptosis in rat chondrocytes via calcium overload and mitochondrial dysfunction

S Yin, L Zhang, L Ding, Z Huang, B Xu, XC Li… - Journal of …, 2018 - Springer
Background Chondrocyte apoptosis is a central feature in the progression of osteoarthritis
(OA), and would be triggered by sustained elevation of intracellular calcium ion (Ca 2+), also …

Research progress on nanotechnology of traditional Chinese medicine to enhance the therapeutic effect of osteoarthritis

Y Peng, Z Yang, J Li, S Liu - Drug Delivery and Translational Research, 2024 - Springer
Osteoarthritis (OA) is a prevalent chronic condition that primarily impacts the articular
cartilage and surrounding bone tissue, resulting in joint inflammation and structural …

Articular Cartilage—From Basic Science Structural Imaging to Non-Invasive Clinical Quantitative Molecular Functional Information for AI Classification and Prediction

B Kurz, T Lange, M Voelker, ML Hart… - International Journal of …, 2023 - mdpi.com
This review presents the changes that the imaging of articular cartilage has undergone
throughout the last decades. It highlights that the expectation is no longer to image the …

Intra-articular injection of umbilical cord mesenchymal stem cells loaded with graphene oxide granular lubrication ameliorates inflammatory responses and …

A Liu, J Chen, J Zhang, C Zhang, Q Zhou… - Frontiers in …, 2022 - frontiersin.org
Aim This study is to investigate the effects of umbilical cord mesenchymal stem cells
(UCMSCs) loaded with the graphene oxide (GO) granular lubrication on ameliorating …