Biomarkers in neonatal hypoxic–ischemic encephalopathy—Review of the literature to date and future directions for research

DM Murray - Handbook of clinical neurology, 2019 - Elsevier
The widespread introduction of therapeutic hypothermia as a standard of care in hypoxic–
ischemic encephalopathy (HIE) has brought increasing pressure on clinicians to make an …

Hypoxic-ischemic encephalopathy: changing outcomes across the spectrum

A Pappas, G Milano, LF Chalak - Clinics in Perinatology, 2023 - perinatology.theclinics.com
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Multichannel EEG abnormalities during the first 6 hours in infants with mild hypoxic–ischaemic encephalopathy

AA Garvey, AM Pavel, JM O'Toole, BH Walsh… - Pediatric …, 2021 - nature.com
Background Infants with mild HIE are at risk of significant disability at follow-up. In the pre-
therapeutic hypothermia (TH) era, electroencephalography (EEG) within 6 hours of birth was …

Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non …

P Montaldo, PJ Lally, V Oliveira, R Swamy… - Archives of Disease in …, 2019 - fn.bmj.com
Objective To examine the effect of therapeutic hypothermia on MR biomarkers and
neurodevelopmental outcomes in babies with mild hypoxic-ischaemic encephalopathy …

[HTML][HTML] Neuroprotective strategies following perinatal hypoxia-ischemia: Taking aim at NOS

M Albrecht, K Zitta, F Groenendaal, F van Bel… - Free Radical Biology …, 2019 - Elsevier
Perinatal asphyxia is characterized by oxygen deprivation and lack of perfusion in the
perinatal period, leading to hypoxic-ischemic encephalopathy and sequelae such as …

[PDF][PDF] Advances in understanding the mechanism of transitional neonatal hypoglycemia and implications for management

DL Stanescu, CA Stanley - Clinics in perinatology, 2022 - Elsevier
100 words). Our lack of basic knowledge about the basic mechanisms of transitional
hypoglycemia and other forms of hypoglycemia in newborns underlies the on-going …

Mood disorders in children following neonatal hypoxic-ischemic encephalopathy

M Álvarez-García, I Cuellar-Flores, P Sierra-García… - PloS one, 2022 - journals.plos.org
Background Few studies on the consequences following newborn hypoxic-ischemic
encephalopathy (NHIE) assess the risk of mood disorders (MD), although these are …

Outcomes in children after mild neonatal hypoxic ischaemic encephalopathy: A population‐based cohort study

AE Törn, S Hesselman, K Johansen… - … Journal of Obstetrics …, 2023 - Wiley Online Library
Objective To investigate whether mild neonatal hypoxic ischaemic encephalopathy (HIE) in
term born infants is associated with cerebral palsy, epilepsy, mental retardation and death …

Creatine in the fetal brain: a regional investigation of acute global hypoxia and creatine supplementation in a translational fetal sheep model

NT Tran, AM Muccini, N Hale, M Tolcos… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Creatine supplementation during pregnancy is a promising prophylactic
treatment for perinatal hypoxic brain injury. Previously, in near-term sheep we have shown …

[HTML][HTML] Neonatal cortical activity organizes into transient network states that are affected by vigilance states and brain injury

M Khazaei, K Raeisi, S Vanhatalo, F Zappasodi… - NeuroImage, 2023 - Elsevier
Early neurodevelopment is critically dependent on the structure and dynamics of
spontaneous neuronal activity; however, the natural organization of newborn cortical …