The time is right to perform a randomized controlled trial (RCT) of neuroprotection for
neonates with mild hypoxic-ischemic encephalopathy (HIE). According to published reports …

Background The Millennium Developmental Goals ensured a significant reduction in
childhood mortality. However, this reduction simultaneously raised concerns about the long …

Background Therapeutic hypothermia is standard of care for babies with moderate/severe
hypoxic-ischaemic encephalopathy and is increasingly used for mild encephalopathy …

Objective To determine the concentrations of four neuroprotein biomarkers and 68 miRNAs
in neonates with low cord pH and/or mild hypoxic-ischemic encephalopathy (HIE). Study …

Objective The use of therapeutic hypothermia (TH) for mild hypoxic–ischaemic
encephalopathy (HIE) remains controversial and inconsistent. We analysed trends in TH …

Brain injury at birth is an important cause of neurological and behavioral disorders. Hypoxic-
ischemic encephalopathy (HIE) is a critical cerebral event occurring acutely or chronically at …

Background Secondary and retrospective use of hospital-hosted clinical data provides a
time-and cost-efficient alternative to prospective clinical trials for biomarker development …

Intellectual disability (ID) affects approximately 1% of the population. Some patients with
severe or profound ID are essentially non-communicating and therefore risk experiencing …

Objective We aimed to evaluate abnormal magnetic resonance imaging (MRI) findings in
neonates with mild hypoxic-ischemic encephalopathy (HIE). Study design This was a single …

Background Autism entails reduced communicative abilities. Approximately 30% of
individuals with autism have intellectual disability (ID). Some people with autism and ID are …