Ovarian cancer (OC) remains a fatal malignancy because most patients experience
recurrent disease, which is resistant to chemotherapy. The outcomes for patients with …

Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple
histological subtypes. Molecular diversity has been shown to occur within specific …

Background Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis,
but the molecular events involved in this transformation have not been described. Methods …

Ovarian clear-cell carcinoma (OCCC) is an aggressive form of ovarian cancer with high
ARID1A mutation rates. Here we present a mutant mouse model of OCCC. We find that …

Ovarian cancer, which ranks fifth in cancer deaths among women, is the most lethal
gynecologic malignancy. Epithelial ovarian cancer (EOC) is the most common histologic …

OBJECTIVES: Recent literature has highlighted histological types of ovarian carcinoma as
distinct diseases, each with unique clinical and molecular features. Historically, the …

OBJECTIVE: Different histologic types of epithelial ovarian cancer may represent different
diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of …

MicroRNAs (miRNAs) are small noncoding RNAs that direct gene regulation through
translational repression and degradation of complementary mRNA. Although miRNAs have …

Endometriosis is a common gynecological disease affecting 6%–10% of women of
reproductive age and is characterized by the presence of endometrial-like tissue in …

Inconsistencies in the half-maximal (50%) inhibitory concentration (IC 50) data for anticancer
chemotherapeutic agents have yielded irreproducible experimental results and thus …