• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic
dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of …

Background The clinical relevance of genetic variants in nonischemic dilated
cardiomyopathy (DCM) is unsettled. Objectives The study sought to assess the prognostic …

Background Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to
5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …

Background Although genotyping allows family screening and influences risk-stratification in
patients with nonischemic dilated cardiomyopathy (DCM) or isolated left ventricular systolic …

Abstract Purpose of Review Sex hormones drive development and function of reproductive
organs or the development of secondary sex characteristics but their effects on the …

Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular
enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a …

Traditional cardiomyopathy paradigms segregate inflammatory etiologies from those caused
by genetic variants. An identified or presumed trigger is implicated in acute myocarditis or …

Purpose Accurate interpretation of variants detected in dilated cardiomyopathy (DCM) is
crucial for patient care but has proven challenging. We applied a set of proposed refined …