Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …

Objective To systematically review published and unpublished efficacy studies of
agomelatine in people with depression. Design Systematic review and meta-analysis. Data …

We now recognise that withdrawal symptoms from antidepressants are common, and can be
severe and long-lasting in some people. Many withdrawal symptoms overlap with symptoms …

Recently, a range of prescription and over-the-counter drugs have been reportedly used as
Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their …

Background: Protracted withdrawal syndrome (PWS) after stopping antidepressants
(frequently also referred to as post-acute withdrawal syndrome or PAWS) has been …

When first published in 1999, Your Drug May Be Your Problem was ahead of its time. The
only book to provide an uncensored description of the dangers involved in taking every kind …

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• More and more countries accept
patient reporting in their spontaneous reporting systems.• Media exposure about drugs can …

Objective: Traditionally, studies on the non-medical use of pharmaceutical products have
focused on controlled substances; eg, opiates/opioids; and benzodiazepines. Although both …

Depression is the most frequent and costly problem in primary care, where most of these
patients are seen and treated. In many countries, the public regard antidepressant drugs as …

As part of our updated series of articles on the major psychiatric drug groups, produced in
association with the College of Mental Health Pharmacy (www. cmhp. org. uk), Stephen …