Synergistic drug combinations from electronic health records and gene expression
YS Low, AC Daugherty, EA Schroeder… - Journal of the …, 2017 - academic.oup.com
Objective: Using electronic health records (EHRs) and biomolecular data, we sought to
discover drug pairs with synergistic repurposing potential. EHRs provide real-world …
discover drug pairs with synergistic repurposing potential. EHRs provide real-world …
Fragmentation of care and colorectal cancer survival in South Korea: comparisons according to treatment at multiple hospitals
Purpose Fragmented cancer care (FC) means that patients visit multiple providers for
treatment, which is common in cancer care. While FC is associated with poor health …
treatment, which is common in cancer care. While FC is associated with poor health …
Artificial intelligence in oncology
Medical decisions can rely on a very large number of parameters, but it is traditionally
considered that our cognitive capacity can only integrate up to five factors in order to take a …
considered that our cognitive capacity can only integrate up to five factors in order to take a …
Hospital transfer after a breast cancer diagnosis: A population-based study in the Netherlands of the extent, predictive characteristics and its impact on time to …
E Heeg, K Schreuder, PER Spronk… - European Journal of …, 2019 - Elsevier
Purpose Patients may transfer of hospital for clinical reasons but this may delay time to
treatment. The purpose of this study is to provide insight in the extent of hospital transfer in …
treatment. The purpose of this study is to provide insight in the extent of hospital transfer in …
Breast cancer learning health system: Patient information from a data and analytics platform characterizes care provided
MN Levine, J Kemppainen, M Rosenberg… - Learning Health …, 2024 - Wiley Online Library
Purpose In a learning health system (LHS), data gathered from clinical practice informs care
and scientific investigation. To demonstrate how a novel data and analytics platform can …
and scientific investigation. To demonstrate how a novel data and analytics platform can …
Capitalizing on central registries for expanded cancer surveillance and research
CJ Bradley, J Entwistle, LM Sabik, RC Lindrooth… - Medical care, 2022 - journals.lww.com
Background: State central cancer registries are an essential component of cancer
surveillance and research that can be enriched through linkages to other databases. This …
surveillance and research that can be enriched through linkages to other databases. This …
Navigating choices when applying multiple imputation in the presence of multi-level categorical interaction effects
Multiple imputation (MI) is an appealing option for handling missing data. When
implementing MI, however, users need to make important decisions to obtain estimates with …
implementing MI, however, users need to make important decisions to obtain estimates with …
Reporting trends and prognostic significance of lymphovascular invasion in muscle‐invasive urothelial carcinoma: A population‐based study
Objectives To investigate reporting patterns and outcomes associated with lymphovascular
invasion in a general population setting. Methods We identified all cystectomy patients with …
invasion in a general population setting. Methods We identified all cystectomy patients with …
[HTML][HTML] Dynamic strategy for personalized medicine: An application to metastatic breast cancer
X Chen, RD Shachter, AW Kurian, DL Rubin - Journal of biomedical …, 2017 - Elsevier
We compare methods to develop an adaptive strategy for therapy choice in a class of breast
cancer patients, as an example of approaches to personalize therapies for individual …
cancer patients, as an example of approaches to personalize therapies for individual …
Benchmark method for cost computations across health care systems: cost of care per patient per day in breast cancer care
DW Blayney, T Seto, N Hoang, C Lindquist… - JCO Oncology …, 2021 - ascopubs.org
PURPOSE: To estimate the value of cancer care and to compare value among episodes of
care, a transparent, reproducible, and standardized cost computation methodology is …
care, a transparent, reproducible, and standardized cost computation methodology is …