Diabetic nephropathy (DN) is one of the most severe complications of diabetes. However,
due to its complex pathological mechanisms, no effective therapeutic methods (other than …

Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of
glucose and metabolites activates resident macrophages in kidneys. Resident macrophages …

Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone
microarchitecture, with an increased risk of fractures. Classical theories hold that …

Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …

Lung macrophages (Mφs) are essential for pulmonary innate immunity and host defense
due to their dynamic polarization and phenotype shifts. Mesenchymal stromal cells (MSCs) …

Background Mesenchymal stromal/stem cells (MSCs) are the most promising stem cells for
the treatment of multiple inflammatory and immune diseases due to their easy acquisition …

Although plenty of drugs are currently available for type 2 diabetes mellitus (T2DM), a subset
of patients still failed to restore normoglycemia. Recent studies proved that symptoms of …

The use of mesenchymal stem cells (MSCs) has become a new strategy for treating diabetic
kidney disease (DKD). However, the role of placenta derived mesenchymal stem cells (P …