Interleukin-12: a cytokine at the interface of inflammation and immunity
G Trinchieri - Advances in immunology, 1998 - Elsevier
Publisher Summary Although interleukin-12 (IL-12) has been discovered only relatively
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
Clinical pharmacology of systemic antifungal agents: a comprehensive review of agents in clinical use, current investigational compounds, and putative targets for …
AH Groll, SC Piscitelli, TJ Walsh - Advances in pharmacology, 1998 - Elsevier
During the past two decades invasive fungal infections have emerged as major causes of
morbidity and mortality in immunocompromised patients. Several factors have contributed to …
morbidity and mortality in immunocompromised patients. Several factors have contributed to …
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with …
U Muller, W Stenzel, G Köhler, C Werner… - The Journal of …, 2007 - journals.aai.org
In the murine model of Cryptococcus neoformans infection Th1 (IL-12/IFN-γ) and Th17 (IL-
23/IL-17) responses are associated with protection, whereas an IL-4-dependent Th2 …
23/IL-17) responses are associated with protection, whereas an IL-4-dependent Th2 …
Interleukin-12 Is Essential for a Protective Th1 Response in Mice Infected with Cryptococcus neoformans
K Decken, G Köhler, K Palmer-Lehmann… - Infection and …, 1998 - Am Soc Microbiol
To analyze the roles of interleukin-12 (IL-12) and the IL-12-dependent Th1 response in
resistance to Cryptococcus neoformans, we have established a chronic infection model in …
resistance to Cryptococcus neoformans, we have established a chronic infection model in …
CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection
TR Traynor, WA Kuziel, GB Toews… - The Journal of …, 2000 - journals.aai.org
Pulmonary clearance of the encapsulated yeast Cryptococcus neoformans requires the
development of T1-type immunity. The objective of this study was to determine the role of …
development of T1-type immunity. The objective of this study was to determine the role of …
Interleukin-12 in infectious diseases
L Romani, P Puccetti, F Bistoni - Clinical microbiology reviews, 1997 - Am Soc Microbiol
Interleukin-12 (IL-12) is a potent immunoregulatory cytokine that is crucially involved in a
wide range of infectious diseases. In several experimental models of bacterial, parasitic …
wide range of infectious diseases. In several experimental models of bacterial, parasitic …
Proinflammatory and immunoregulatory functions of interleukin-12
G Trinchieri - International reviews of immunology, 1998 - Taylor & Francis
Interleukin-12 (IL-12) is a cytokine composed of two chains, a heavy chain or p40, and a
light chain or p35, forming a disulfite-linked heterodimer, or p70. IL-12 was originally …
light chain or p35, forming a disulfite-linked heterodimer, or p70. IL-12 was originally …
Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment
FP Gullo, SA Rossi, JCO Sardi, VLI Teodoro… - European journal of …, 2013 - Springer
Cryptococcosis is an important systemic mycosis and the third most prevalent disease in
human immunodeficiency virus (HIV)-positive individuals. The incidence of cryptococcosis is …
human immunodeficiency virus (HIV)-positive individuals. The incidence of cryptococcosis is …
Chitin synthesis in human pathogenic fungi
In recent years it has become evident that the structural polysaccharide chitin is synthesized
from a family of enzymes encoded by multiple CHS chitin synthase genes, and regulated by …
from a family of enzymes encoded by multiple CHS chitin synthase genes, and regulated by …
[HTML][HTML] Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections
CML Wager, FL Wormley Jr - Mucosal immunology, 2014 - Elsevier
Macrophages are innate immune cells that possess unique abilities to polarize toward
different phenotypes. Classically activated macrophages are known to have major roles in …
different phenotypes. Classically activated macrophages are known to have major roles in …