Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea
JK Mueller, WE Müller - Journal of Neural Transmission, 2024 - Springer
Cognitive impairment, depression and (mental) fatigue represent the most frequent
neuropsychiatric symptoms of the post-COVID syndrome. Neuroinflammation, oxidative …
neuropsychiatric symptoms of the post-COVID syndrome. Neuroinflammation, oxidative …
Tryptophan catabolites, inflammation, and insulin resistance as determinants of chronic fatigue syndrome and affective symptoms in long COVID
HK Al-Hakeim, A Khairi Abed… - Frontiers in Molecular …, 2023 - frontiersin.org
Critical COVID-19 disease is accompanied by depletion of plasma tryptophan (TRY) and
increases in indoleamine-dioxygenase (IDO)-stimulated production of neuroactive …
increases in indoleamine-dioxygenase (IDO)-stimulated production of neuroactive …
Reactivation of herpesvirus type 6 and IgA/IgM-mediated responses to activin-A underpin long COVID, including affective symptoms and chronic fatigue syndrome
A Vojdani, AF Almulla, B Zhou, HK Al-Hakeim… - Acta …, 2024 - cambridge.org
Background: Persistent infection with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), reactivation of dormant viruses, and immune-oxidative responses are …
(SARS-CoV-2), reactivation of dormant viruses, and immune-oxidative responses are …
Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms.
AF Almulla, M Maes, B Zhou, H Al-Hakeim, A Vojdani - medRxiv, 2023 - medrxiv.org
Background: Autoimmune responses contribute to the pathophysiology of Long COVID,
affective symptoms and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) …
affective symptoms and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) …
In major dysmood disorder, physiosomatic, chronic fatigue and fibromyalgia symptoms are driven by immune activation and increased immune-associated …
M Maes, AF Almulla, B Zhou, AAA Algon, P Sodsai - Scientific Reports, 2024 - nature.com
Major depressive disorder (MDD) is accompanied by activated neuro-immune pathways,
increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The most severe …
increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The most severe …
T cell activation and deficits in T regulatory cells are associated with major depressive disorder and severity of depression
M Rachayon, K Jirakran, P Sodsai… - Scientific Reports, 2024 - nature.com
Major depressive disorder (MDD) is associated with T cell activation, but no studies have
examined the combined effects of T cell activation and deficits in T regulatory (Treg) cells on …
examined the combined effects of T cell activation and deficits in T regulatory (Treg) cells on …
Neuropsychiatric and neurodegenerative aspects of acute and long COVID
AF Almulla, HK Al-Hakeim - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
The escalating prevalence of central nervous system (CNS) symptoms during acute stage
and 3–6 months after coronavirus disease (COVID-19), termed “Long COVID disease,” is a …
and 3–6 months after coronavirus disease (COVID-19), termed “Long COVID disease,” is a …
Increased galanin-galanin receptor 1 signaling, inflammation, and insulin resistance are associated with affective symptoms and chronic fatigue syndrome due to …
WTM Al-Masoodi Sr, SW Radhi, HK Abdalsada, M Niu… - medRxiv, 2024 - medrxiv.org
Background. Long COVID (LC) patients frequently suffer from neuropsychiatric symptoms,
including depression, anxiety, and chronic fatigue syndrome (CFS), relabeled as the physio …
including depression, anxiety, and chronic fatigue syndrome (CFS), relabeled as the physio …
In severe first episode major depressive disorder, psychosomatic, chronic fatigue syndrome, and fibromyalgia symptoms are driven by immune activation and …
Background: Major depressive disorder (MDD) is accompanied by activated neuro-immune
pathways, increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The …
pathways, increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The …
Cognitive Impairment under Prolonged Social Isolation: Insights from Human Studies and Animal Experiments
NA Krupina, SD Shirenova - Uspehi fiziologičeskih nauk, 2023 - journals.rcsi.science
Having close social connections is essential for mental and physical health and overall well-
being, regardless of age. A considerable portion of the world's population has experienced …
being, regardless of age. A considerable portion of the world's population has experienced …