Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility

NL Smith, AL Wilson, J Gandhi, S Vatsia… - Medical gas …, 2017 - journals.lww.com
The use of ozone (O 3) gas as a therapy in alternative medicine has attracted skepticism due
to its unstable molecular structure. However, copious volumes of research have provided …

Antimicrobial strategies centered around reactive oxygen species–bactericidal antibiotics, photodynamic therapy, and beyond

F Vatansever, WCMA de Melo, P Avci… - FEMS microbiology …, 2013 - academic.oup.com
Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial
activity, which accounts for their versatility in mediating host defense against a broad range …

The effects of oxygen–ozone therapy on regulatory T‐cell responses in multiple sclerosis patients

S Tahmasebi, MT Qasim, MV Krivenkova… - Cell biology …, 2021 - Wiley Online Library
Multiple sclerosis (MS) is a common degenerative disorder of the central nervous system.
The decreased frequency and dysfunction of Treg cells cause inflammation and disease …

The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology

DB Graves - Journal of Physics D: Applied Physics, 2012 - iopscience.iop.org
Reactive oxygen species (ROS) and the closely related reactive nitrogen species (RNS) are
often generated in applications of atmospheric pressure plasmas intended for biomedical …

[HTML][HTML] Non-thermal atmospheric-pressure plasma possible application in wound healing

B Haertel, T Von Woedtke, KD Weltmann… - Biomolecules & …, 2014 - ncbi.nlm.nih.gov
Non-thermal atmospheric-pressure plasma, also named cold plasma, is defined as a partly
ionized gas. Therefore, it cannot be equated with plasma from blood; it is not biological in …

Contaminant-induced oxidative stress in fish: a mechanistic approach

VI Lushchak - Fish physiology and biochemistry, 2016 - Springer
The presence of reactive oxygen species (ROS) in living organisms was described more
than 60 years ago and virtually immediately it was suggested that ROS were involved in …

Potential cytoprotective activity of ozone therapy in SARS-CoV-2/COVID-19

G Martínez-Sánchez, A Schwartz, V Di Donna - Antioxidants, 2020 - mdpi.com
(1) Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) disease (COVID-19) in China at the end of 2019 has caused a large global outbreak …

Hydroxyl radical and its scavengers in health and disease

B Lipinski - Oxidative medicine and cellular longevity, 2011 - Wiley Online Library
It is generally believed that diseases caused by oxidative stress should be treated with
antioxidants. However, clinical trials with such antioxidants as ascorbic acid and vitamin E …

Oxygen–Ozone therapy in the rehabilitation field: state of the art on mechanisms of action, safety andeffectiveness in patients with musculoskeletal disorders

A de Sire, F Agostini, L Lippi, M Mangone, S Marchese… - Biomolecules, 2021 - mdpi.com
In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …

Mechanisms of action involved in ozone-therapy in skin diseases

J Zeng, J Lu - International immunopharmacology, 2018 - Elsevier
Ozone-therapy initially applied in medicine by an empirical approach, has now reached a
new stage where most of the biological mechanisms of ozone action have been clarified …