[HTML][HTML] Porphyromonas gingivalis FimA and Mfa1 fimbriae: Current insights on localization, function, biogenesis, and genotype
Y Hasegawa, K Nagano - Japanese Dental Science Review, 2021 - Elsevier
In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct FimA and
Mfa1 fimbriae. Each of these consists of five FimA–E and five Mfa1–5 proteins encoded by …
Mfa1 fimbriae. Each of these consists of five FimA–E and five Mfa1–5 proteins encoded by …
An investigation into the effects of outer membrane vesicles and lipopolysaccharide of Porphyromonas gingivalis on blood-brain barrier integrity, permeability, and …
AB Pritchard, Z Fabian, CL Lawrence… - Journal of …, 2022 - content.iospress.com
Background: The effects of the key pathogens and virulence factors associated with gum
disease such as Porphyromonas gingivalis (P. gingivalis) on the central nervous system is of …
disease such as Porphyromonas gingivalis (P. gingivalis) on the central nervous system is of …
Periodontitis associates with species-specific gene expression of the oral microbiota
D Belstrøm, F Constancias, DI Drautz-Moses… - npj Biofilms and …, 2021 - nature.com
The purpose of the present investigation was to characterize species-specific bacterial
activity of the oral microbiota in periodontitis. We tested the hypotheses that chronic …
activity of the oral microbiota in periodontitis. We tested the hypotheses that chronic …
[HTML][HTML] Porphyromonas gingivalis outer membrane vesicles modulate cytokine and chemokine production by gingipain-dependent mechanisms in human …
Objective The aim was to determine the changes of inflammatory mediator expression in
human macrophages stimulated with outer membrane vesicles purified from …
human macrophages stimulated with outer membrane vesicles purified from …
Exploring the genetic and functional diversity of Porphyromonas gingivalis long fimbriae
HL Meyer, MMH Abdelbary, EM Buhl… - Molecular Oral …, 2023 - Wiley Online Library
Porphyromonas gingivalis is a key pathobiont in periodontitis. Its long fimbriae consist of a
single anchor (FimB), a varying number of stalk (FimA), and three accessory (tip‐related) …
single anchor (FimB), a varying number of stalk (FimA), and three accessory (tip‐related) …
A quantitative framework reveals traditional laboratory growth is a highly accurate model of human oral infection
Bacterial behavior and virulence during human infection is difficult to study and largely
unknown, as our vast knowledge of infection microbiology is primarily derived from studies …
unknown, as our vast knowledge of infection microbiology is primarily derived from studies …
Strain-level variation and diverse host bacterial responses in episymbiotic Saccharibacteria
ABSTRACT Saccharibacteria (TM7), which are obligate episymbionts growing on the
surface of host bacteria, may play an important role in oral disease, such as periodontitis (1 …
surface of host bacteria, may play an important role in oral disease, such as periodontitis (1 …
Comparative analysis of Porphyromonas gingivalis A7436 and ATCC 33277 strains reveals differences in the expression of heme acquisition systems
M Śmiga, P Ślęzak, T Olczak - Microbiology Spectrum, 2024 - Am Soc Microbiol
Porphyromonas gingivalis strains exhibit different phenotypes in vitro, different virulence
potential in animal models, and different associations with human diseases, with strains …
potential in animal models, and different associations with human diseases, with strains …
Inhibitory effect of Porphyromonas gingivalis‐derived phosphoethanolamine dihydroceramide on acid ceramidase expression in oral squamous cells
C Yamada, A Ho, A Nusbaum, R Xu… - Journal of Cellular …, 2023 - Wiley Online Library
The maintenance of diminished acid ceramidase (ASAH1) gene expression leading to the
accumulation of antiproliferative intracellular ceramides in oral squamous cell carcinoma …
accumulation of antiproliferative intracellular ceramides in oral squamous cell carcinoma …
Nicotinamide employs a starvation strategy against Porphyromonas gingivalis virulence by inhibiting the heme uptake system and gingipain activities
Z Lei, Q Ma, Y Tu, Y Qiu, T Gong, Y Lin… - Molecular Oral …, 2024 - Wiley Online Library
Periodontitis is a common oral bacterial infection characterized by inflammatory responses.
Its high prevalence lowers the quality of life for individuals and increases the global …
Its high prevalence lowers the quality of life for individuals and increases the global …