[HTML][HTML] Cartilage and bone destruction in arthritis: pathogenesis and treatment strategy: a literature review

D Tateiwa, H Yoshikawa, T Kaito - Cells, 2019 - mdpi.com
Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …

Selective Tyk2 inhibitors as potential therapeutic agents: a patent review (2015–2018)

X He, X Chen, H Zhang, T Xie, XY Ye - Expert Opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction: Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine-protein kinase,
an enzyme that in humans is encoded by the TYK2 gene. Tyk2, together with three other …

[HTML][HTML] Horizon scan: State-of-the-art therapeutics for psoriatic arthritis

J Hutton, P Mease, D Jadon - Best Practice & Research Clinical …, 2022 - Elsevier
Psoriatic arthritis (PsA) is a common immune-mediated inflammatory disease (IMID) that can
present with a heterogenous clinical phenotype. The advent of advanced therapies has …

[HTML][HTML] Real-world evidence of biologic treatments in psoriatic arthritis in Italy: results of the CHRONOS (EffeCtiveness of biologic treatments for psoriatic artHRitis in …

D Colombo, M Frassi, G Pagano Mariano, E Fusaro… - BMC rheumatology, 2022 - Springer
Background Biologics have demonstrated efficacy in PsA in randomized clinical trials. More
evidence is needed on their effectiveness under real clinical practice conditions. The aim of …

Assessment of serum and synovial fluid MMP-3 and MPO as biomarkers for psoriatic arthritis and their relation to disease activity indices

M Geneva-Popova, S Popova-Belova… - Rheumatology …, 2022 - Springer
Research on biomarkers for the diagnosis and monitoring of psoriatic arthritis (PsA) is
ongoing. The purpose of this study was to assess the potential of serum and synovial fluid …

CSF nerve growth factor (β-NGF) is increased but CSF insulin-like growth factor-(IGF-1) is normal in children with tuberous sclerosis and infantile spasms

R Riikonen, H Kokki - European Journal of Paediatric Neurology, 2019 - Elsevier
Tuberous sclerosis is associated with epilepsy that is often refractory. We examined
cerebrospinal fluid (CSF) concentrations for neurotrophins, nerve growth factor (β-NGF) and …

Targeted synthetic pharmacotherapy for psoriatic arthritis: state of the art

F Caso, L Navarini, P Ruscitti, MS Chimenti… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction In recent years, different studies regarding psoriatic arthritis (PsA) have shown
the pathogenetic role of dysfunction of signaling pathways involving the phosphodiesterase …

Limits of traditional evidence-based medicine methodologies exemplified by the novel era in psoriatic arthritis drug development

EF Leijten, TR Radstake, IB McInnes… - Expert Review of …, 2019 - Taylor & Francis
An array of new and expensive drugs recently entered the market for psoriatic arthritis (PsA),
and several soon will follow, joining the already rich armamentarium [1, 2]. As a …

Therapie der Psoriasisarthritis unter Berücksichtigung neuer Behandlungsoptionen

C Ryser, A Ciurea - Praxis, 2018 - econtent.hogrefe.com
Die Psoriasisarthritis wird bei ca. 20–30% der Patienten mit Psoriasis vulgaris diagnostiziert
und weist ein heterogenes Erscheinungsbild auf. Die Therapie richtet sich nach den …

Twenty years without treatment: a presentation of arthritis mutilans with psoriasis

Y Qin, RA Beach - Journal of Cutaneous Medicine and …, 2019 - journals.sagepub.com
Twenty Years Without Treatment: A Presentation of Arthritis Mutilans With Psoriasis - Yang
Qin, Renée A. Beach, 2019 Skip to main content Intended for healthcare professionals …