Antibiotic resistance is an urgent public health threat that has received substantial attention
from the world's leading health agencies and national governmental bodies alike. However …

Bloodstream infections (BSIs) are among the leading infections in critically ill patients. The
case-fatality rate associated with BSIs in patients admitted to intensive care units (ICUs) …

Repeated use of xenobiotic chemicals has selected for the rapid evolution of resistance,
threatening health and food security at a global scale. Strategies for preventing the evolution …

The US health care system has remained a complex puzzle to many Americans and the new
health reform legislation will doubtless add additional complexity to the puzzle. Medical care …

The global health threat surrounding bacterial resistance has resulted in antibiotic
researchers shifting their focus away from 'traditional'antibiotics and concentrating on other …

Background Conducted as part of the Driving Reinvestment in Research and Development
and Responsible Antibiotic Use (DRIVE-AB) project, this study aimed to identify key …

Extended-spectrum beta-lactamase (ESBL)-and carbapenemase (CP)-producing Klebsiella
pneumoniae isolates are a public health concern at clinical level, mainly in Southern …

Peptide arrays on cellulose are a powerful tool to investigate peptide interactions with a
number of different molecules, for examples antibodies, receptors or enzymes. Such peptide …

Antibiotic resistance in pathogens is a growing threat to human health. Of particular concern
is resistance to carbapenem, which is an antimicrobial agent listed as critically important by …

The review is devoted to the latest achievements in the design of dual action antibiotics—
heterodimeric (chimeric) structures based on antibacterial agents of different classes …