Chemically modified platforms for better RNA therapeutics

Y Shi, X Zhen, Y Zhang, Y Li, S Koo, Q Saiding… - Chemical …, 2024 - ACS Publications
RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

[HTML][HTML] Nanotechnology-assisted biosensors for the detection of viral nucleic acids: An Overview

HK Choi, J Yoon - Biosensors, 2023 - mdpi.com
The accurate and rapid diagnosis of viral diseases has garnered increasing attention in the
field of biosensors. The development of highly sensitive, selective, and accessible …

A universal and specific RNA biosensor via DNA circuit-mediated PAM-independent CRISPR/Cas12a and PolyA-rolling circle amplification

S Wang, H Li, K Dong, W Shu, J Zhang, J Zhang… - Biosensors and …, 2023 - Elsevier
Point of care testing (POCT) has important clinical significance for the diagnosis and
prognosis evaluation of diseases. At present, the biosensor based on CRISPR/Cas12a has …

[HTML][HTML] Functional nucleic acid-based biosensors for virus detection

Z Zhang, BR Adhikari, P Sen, L Soleymani, Y Li - Advanced Agrochem, 2023 - Elsevier
A growing number of viruses pose significant threats to human health, impact agricultural
production and compromise food safety. Minimizing the impact of viral infections demands …

Recent developments in DNA nanostructure-based biosensors for the detection of melamine adulteration in milk

F Shalileh, H Sabahi, M Golbashy, M Dadmehr… - Microchemical …, 2023 - Elsevier
Due to the remarkable impact of food safety on public health, accurate food safety
surveillance is a major issue in the food industry. The increasing trend of the world …

Application of intelligent responsive DNA self-assembling nanomaterials in drug delivery

H Ji, Q Zhu - Journal of Controlled Release, 2023 - Elsevier
Smart nanomaterials are nano-scaled materials that respond in a controllable and reversible
way to external physical or chemical stimuli. DNA self-assembly is an effective way to …

DNA/RNA-based electrochemical nanobiosensors for early detection of cancers

B Mikaeeli Kangarshahi, SM Naghib… - Critical reviews in …, 2024 - Taylor & Francis
Nucleic acids, like DNA and RNA, serve as versatile recognition elements in electrochemical
biosensors, demonstrating notable efficacy in detecting various cancer biomarkers with high …

Simple and multiplexed detection of nucleic acid targets based on fluorescent ring patterns and deep learning analysis

J Lee, T Lee, HN Lee, H Kim, YK Kang… - … Applied Materials & …, 2023 - ACS Publications
Simple diagnostic tests for nucleic acid targets can provide great advantages for
applications such as rapid pathogen detection. Here, we developed a membrane assay for …

[HTML][HTML] Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …

Hyperbranched RCA-mediated construction of a dendritic DNA nanostructure for ratiometric fluorescence biosensing

P Liang, J Li, Z Pi, X Zhang, X Yu, G Lai - Sensors and Actuators B …, 2024 - Elsevier
As a robust isothermal strand amplification technique, rolling circle amplification (RCA) is
popularly adopted for constructing various homogeneous fluorescence biosensing …