Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

Significance: Diabetic cardiomyopathy (DCM) is a frequent complication occurring even in
well-controlled asymptomatic diabetic patients, and it may advance to heart failure (HF) …

Abstract Background Salvianolic acid B (Sal B) is the representative component of phenolic
acids derived from the dried root and rhizome of Salvia miltiorrhiza Bge.(Labiatae), which …

Diabetic cardiomyopathy (DCM) has been increasingly considered as a main cause of heart
failure and death in diabetic patients. At present, no effective treatment exists to prevent its …

Myocardial infarction (MI), characterized by interruption of blood and oxygen to myocardium,
is a common yet fatal cardiovascular event that causes progressive damage to myocardial …

Poly (ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the
therapy of several types of cancers not responding to conventional treatments. However, de …

Aims Absent in melanoma 2 (AIM2) is a cytosolic DNA sensor which plays an important role
in inflammasome formation and is involved in various cellular functions including pyroptosis …

Andrographolide (Andro), a major bioactive component obtained from Andrographis
paniculata Nees, has exerted wide antioxidant as well as cytoprotective properties …

As the powerhouse of the cells, mitochondria play a very important role in ensuring that cells
continue to function. Mitochondrial dysfunction is one of the main factors contributing to the …

Signaling cascades provide integrative and interactive frameworks that allow the cell to
respond to signals from its environment and/or from within the cell itself. The dynamic …