Excess body weight is frequently associated with low-grade inflammation. Evidence
indicates a relationship between obesity and cancer, as well as with other diseases, such as …

Abstract Background Approximately 70% of Alzheimer's disease (AD) patients have co-
morbid vascular contributions to cognitive impairment and dementia (VCID); this highly …

Neurodegenerative diseases and their associated cognitive decline are known to be more
prevalent during aging. Recent evidence has uncovered the role of microglia, the …

Background Accumulating evidence infer that gut microbiome-host relations are key
mediators or modulators driving the observed sexual dimorphism in some disease onset …

Increasing evidence supports that age, APOE and sex interact to modulate Alzheimer's
disease (AD) risk, however the underlying pathways are unclear. One way that AD risk …

Given the aging population, it is important to better understand neurodegeneration in aging
healthy people and to address the increasing incidence of neurodegenerative diseases. It is …

Patients with cholestatic liver disease, including those with primary biliary cholangitis, can
experience symptoms of impaired cognition or brain fog. This phenomenon remains …

The incidence of sporadic Alzheimer's disease (AD) is increasing in recent years. Studies
have shown that in addition to some genetic abnormalities, the majority of AD patients has a …

Peripheral metabolic disturbances are associated with a variety of clinical health
consequences and may contribute to the development of neurocognitive disorders. This …

Background: Prenatal alcohol exposure (PAE) causes behavioral deficits and increases risk
of metabolic diseases. Alzheimer's Disease (AD) is a neurodegenerative disease that has a …