Crude leaf extracts of Piperaceae species downmodulate inflammatory responses by human monocytes

AC Finato, TF Fraga-Silva, AUC Prati… - PloS one, 2018 - journals.plos.org
In this study, we aimed to evaluate the immunomodulatory effects of crude leaf extracts from
Piper gaudichaudianum Kunth, P. arboreum Aub., P. umbellata L., P. fuligineum Kunth, and …

Flavonas, lignanas e terpeno de Piper umbellata (Piperaceae)

DC Baldoqui, VS Bolzani, M Furlan, MJ Kato… - Química …, 2009 - SciELO Brasil
The phytochemical investigation of Piper umbellata leaves yielded nine compounds
including one terpenoid glucoside, five flavones (vitexin 2"-O-β-glucopyranoside, apigenin 8 …

The lignan eudesmin extracted from Piper truncatum induced vascular relaxation via activation of endothelial histamine H1 receptors

JM Raimundo, APF Trindade, LSM Velozo… - European journal of …, 2009 - Elsevier
In Brazilian folk medicine, extracts from Piper species are used to reduce blood pressure.
Previously, we demonstrated the vasodilatory activity of crude extracts from leaves of Piper …

New lignans from the roots of Schisandra sphenanthera

K Jiang, QY Song, SJ Peng, QQ Zhao, GD Li, Y Li… - Fitoterapia, 2015 - Elsevier
Abstract Nine new lignans (1–8, 13) and five known ones (9–12, 14) have been isolated
from the roots of Schisandra sphenanthera and were tested for their capacity to scavenge 2 …

[PDF][PDF] Genus Nectandra:" Phytochemistry and Biological Activity"

VE Macías-Villamizar, LE Cuca-Suárez… - … Latinoamericano y del …, 2015 - redalyc.org
El género Nectandra pertenece al complejo Ocotea y estas especi es (Nectandra) son por lo
general árboles. Se considera endémica en el Neotrópico. Este género se ha informado de …

Natural products: Key prototypes to drug discovery against neglected diseases caused by trypanosomatids

MT Varela, JPS Fernandes - Current medicinal chemistry, 2020 - ingentaconnect.com
Background: Neglected tropical diseases are a group of infections caused by
microorganisms and viruses that affect mainly poor regions of the world. In addition, most …

Configuration and stability of naturally occurring all-cis-tetrahydrofuran lignans from Piper solmsianum

CS Ramos, HV Linnert, MM de Moraes, JH do Amaral… - RSC …, 2017 - pubs.rsc.org
The study of variability of the tetrahydrofuran lignan (−)-grandisin in leaves of Piper
solmsianum (Piperaceae) revealed two unknown compounds, that were isolated and …

[PDF][PDF] Importance of a multidisciplinary evaluation of Piper genus for development of new natural products in Latin America

A Cáceres, MJ Kato - International Journal of Phytocosmetics and …, 2014 - researchgate.net
Piper species are basal angiosperms used by men as condiment and medicine since
ancient times, and can be easily found in tropical and subtropical forest of America. This mini …

Age-dependent changes from allylphenol to prenylated benzoic acid production in Piper gaudichaudianum Kunth

AM Gaia, LF Yamaguchi, CS Jeffrey, MJ Kato - Phytochemistry, 2014 - Elsevier
HPLC-DAD and principal component analysis (PCA) of the 1 H NMR spectrum of crude
plant extracts showed high chemical variability among seedlings and adult organs of Piper …

In vitro metabolism study of the promising anticancer agent the lignan (−)-grandisin

GB Messiano, RA da Silva Santos, LDS Ferreira… - … of pharmaceutical and …, 2013 - Elsevier
The lignan (−)-grandisin has shown important pharmacological activities, such as citotoxicity
and antiangiogenic, antibacterial and trypanocidal activities. So, it has been considered as a …