In vitro metabolism of the lignan (−)‐grandisin, an anticancer drug candidate, by human liver microsomes
T Barth, MD Habenschus, F Lima Moreira… - Drug Testing and …, 2015 - Wiley Online Library
(−)‐grandisin is a tetrahydrofuran lignan that displays important biological properties, such
as trypanocidal, anti‐inflammatory, cytotoxic, and antitumor activities, suggesting its utility as …
as trypanocidal, anti‐inflammatory, cytotoxic, and antitumor activities, suggesting its utility as …
Essential Oil Constituents of Piper vicosanum Yunker from the Brazilian Atlantic Forest
JMO Mesquita, AB Oliveira, FC Braga… - Journal of Essential …, 2006 - Taylor & Francis
The composition of Piper vicosanum Yuncker leaf essential oil from the Brazilian Atlantic
Forest (Parque Estadual do Rio Doce, Minas Gerais, Brazil) was investigated. GC and …
Forest (Parque Estadual do Rio Doce, Minas Gerais, Brazil) was investigated. GC and …
Caldensinic acid, a prenylated benzoic acid from Piper caldense
The CH2Cl2 and MeOH extracts from leaves of Piper caldense were subjected to
chromatographic separation procedures to afford the new prenylated benzoic acid …
chromatographic separation procedures to afford the new prenylated benzoic acid …
Chemoprotective effect of the tetrahydrofuran lignan grandisin in the in-vivo rodent micronucleus assay
MC Valadares, LM de Oliveira Júnior… - Journal of Pharmacy …, 2011 - academic.oup.com
Objectives The chemoprotective effect of the tetrahydrofuran lignan grandisin against DNA
damage induced by cyclophosphamide (200 mg/kg) has been evaluated using the in vitro …
damage induced by cyclophosphamide (200 mg/kg) has been evaluated using the in vitro …
[PDF][PDF] Efecto de los extractos de hojas de plantas sobre los parámetros fisiológicos y la microbiología intestinal de pollos parrilleros
X Beteta Blas - 2023 - repositorio.unas.edu.pe
En la actualidad, los residuos de antibióticos en alimentos de origen animal, la resistencia
antimicrobiana de microorganismos, la amplia demanda de fármacos veterinarios, el …
antimicrobiana de microorganismos, la amplia demanda de fármacos veterinarios, el …
Disruption of Chrysomya megacephala Growth Caused by Lignan Grandisin
CDR Nogueira, RP De Mello, MJ Kato… - Journal of medical …, 2009 - academic.oup.com
The toxicity of tetrahydrofuran lignan grandisin was evaluated against larvae of Chrysomya
megacephala F.(Diptera: Calliphoridae). The bioassay involved topical treatment on larvae …
megacephala F.(Diptera: Calliphoridae). The bioassay involved topical treatment on larvae …
[PDF][PDF] Antitrypanosomal agents from higher plants
WN Setzer, MC Setzer - Biologically active natural products for the …, 2006 - researchgate.net
Parasitic protozoal infections such as trypanosomiasis continue to be a great cause of
human morbidity and mortality. African sleeping sickness (African trypanosomiasis) is a re …
human morbidity and mortality. African sleeping sickness (African trypanosomiasis) is a re …
[HTML][HTML] Grandisin induces apoptosis in leukemic K562 cells
AP Cortez, EGP Menezes, PL Benfica… - Brazilian Journal of …, 2017 - SciELO Brasil
In this study, the potential antileukemic activity of grandisin, a lignan extracted from Piper
solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin …
solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin …
Six New Phenolic Glycosides and a New Ceramide from the Flowers of Wedelia biflora and Their Cytotoxicity Against Some Cancer Cell Lines
The plant Wedelia biflora has been used in traditional medicine in India and Vietnam to treat
various symptoms. However, the chemical composition of its flowers remains mostly …
various symptoms. However, the chemical composition of its flowers remains mostly …